DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4839 and prkar1aa

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	NP_001009989.1	Gene:	prkar1aa / 494533	ZFINID:	ZDB-GENE-050116-2	Length:	379	Species:	Danio rerio

Alignment Length:	337	Identity:	97/337 - (28%)
Similarity:	158/337 - (46%)	Gaps:	21/337 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   334 LHLRKKRSMERQQQQKQQEQQQQQEIQQDATNSQDQMAGAEESHKSSDSSTPKTHRVEGGLIYVR 398
            |.|.:.:.|..||:...:...::.|:       ...|....:..:...:.:.:.:..|....|||
Zfish    56 LELEEAKQMVSQQKSSSRSDSREDEV-------SPPMNPVVKGRRRRGAISAEVYTEEDATSYVR 113

  Fly   399 PNFPIQSDIEIESIAKDEGTRNLIRTAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREH 463
            ...|           ||..|...:..|||:|....:|.|.||.: :.:||...:|.....:|::.
Zfish   114 KVIP-----------KDYKTMAALAKAIEKNVLFAHLDDNERSD-IFDAMFSVTYIAGETVIQQG 166

  Fly   464 EEGSEIYVSAEGQYDVIRGGQLVASFGPATVFGELAILYNAPRQASIEAATDARVWKIARETFRA 528
            :||...||..:|:.||....:.|.|.|....|||||::|..||.|::.|.|:.::|.|.|:::|.
Zfish   167 DEGDNFYVIDQGEMDVYVNNEWVTSIGEGGSFGELALIYGTPRAATVRAKTNVKLWGIDRDSYRR 231

  Fly   529 IMQISGSREREENLQFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCG 593
            |:..|..|:|:...:||.....|:..|:...|.|.|.|:...:|....||.:|:.|:||:||..|
Zfish   232 ILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALETVQFEDGQKIVVQGQPGDEFFIILEG 296

  Fly   594 TVTIKKLDEQQQEQIVANR-KRGDYFGEQALLNADVRQASVYADAPGTEVLMLDREAFISYLGTI 657
            :..:.:...:.:|.:...| ...|||||.|||....|.|:|.|..| .:.:.|||..|...||..
Zfish   297 SAAVLQRRSENEEFVEVGRLAPSDYFGEIALLMNRPRAATVVARGP-LKCVKLDRPRFERVLGPC 360

  Fly   658 KQLREKPSSQRN 669
            ..:.::...|.|
Zfish   361 SDILKRNIQQYN 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736	47/148 (32%)
		CAP_ED	431..539	CDD:237999	36/107 (34%)
		Crp	544..>650	CDD:223736	36/106 (34%)
		CAP_ED	550..663	CDD:237999	37/113 (33%)
		S_TKc	695..951	CDD:214567
		STKc_cGK	700..957	CDD:270724
prkar1aa	NP_001009989.1	DD_RIalpha_PKA	14..62	CDD:213048	2/5 (40%)
		Crp	129..>255	CDD:223736	43/126 (34%)
		CAP_ED	135..244	CDD:237999	37/109 (34%)
		Crp	247..>357	CDD:223736	37/110 (34%)
		CAP_ED	253..368	CDD:237999	37/115 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810