DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4839 and Prkar2b

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	NP_001025191.1	Gene:	Prkar2b / 24679	RGDID:	3394	Length:	416	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	91/323 - (28%)
Similarity:	161/323 - (49%)	Gaps:	23/323 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   356 QQEIQQDATNSQDQMAGAEESHKSSDSSTPKTHR-VEGGLIYVRPNFPIQSDIEIES---IAKDE 416
            ::.::.|:.|.::     ||:.::...:.|..:| .....:......|.:.:.:.||   ..|.:
  Rat    78 EEPMRSDSENGEE-----EEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTD 137

  Fly   417 GTRNLIRTAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVI- 480
            ..||.::.|.:......|| |.|:...|::||.....::...:|.:.::|...||...|.:|:.
  Rat   138 DQRNRLQEACKDILLFKNL-DPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV 201

  Fly   481 ---RGGQLVASFGPATVFGELAILYNAPRQASIEAATDARVWKIARETFRAIMQISGSREREENL 542
               ..|:.|.::.....|||||::||.||.|:|.|.:...:|.:.|.|||.|:..:.:::|:...
  Rat   202 KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYE 266

  Fly   543 QFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTV--TIKKLDEQQQ 605
            .|:.|.|||:..:.|..|||||::..|.|.....|:.:|:..:.|:|:..|.|  |:|:..:...
  Rat   267 SFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDI 331

  Fly   606 EQ----IVANRKRGDYFGEQALLNADVRQASVYADAPGT-EVLMLDREAFISYLGTIKQLREK 663
            |:    .:|...||.||||.||:....|.||  |.|.|| :.|.:|.:||...||...::.::
  Rat   332 EENGAVEIARCLRGQYFGELALVTNKPRAAS--AHAIGTVKCLAMDVQAFERLLGPCMEIMKR 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736	47/152 (31%)
		CAP_ED	431..539	CDD:237999	33/111 (30%)
		Crp	544..>650	CDD:223736	40/112 (36%)
		CAP_ED	550..663	CDD:237999	41/119 (34%)
		S_TKc	695..951	CDD:214567
		STKc_cGK	700..957	CDD:270724
Prkar2b	NP_001025191.1	Dimerization and phosphorylation	2..151		13/77 (17%)
		DD_RIIbeta_PKA	3..43	CDD:213051
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	53..97		4/23 (17%)
		CAP_ED	152..265	CDD:237999	34/113 (30%)
		CAP_ED	274..394	CDD:237999	41/121 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810