DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4839 and Prkx

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	NP_058675.1	Gene:	Prkx / 19108	MGIID:	1309999	Length:	355	Species:	Mus musculus

Alignment Length:	358	Identity:	134/358 - (37%)
Similarity:	202/358 - (56%)	Gaps:	30/358 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   656 TIKQ-----LREKPSSQRNDTSGRSSTKSLEFDNEYSQVAISELKKIATLGCGAFGRVDLV--AY 713
            |:|.     ::.|.|:...|...|:|::.       :..::.:...|||:|.|.||||:||  ..
Mouse    10 TVKDPDHDPVKTKVSAPAADPKPRTSSQK-------AGHSLQDWDTIATVGTGTFGRVNLVKEKT 67

  Fly   714 NQQALALKIIKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDV 778
            .:|..||||:...:|::..|.:||.|||.| :|....||:::|..|..:::::|.|||...||::
Mouse    68 GRQYCALKIMSIPDVIRLKQEQHVQNEKAV-LKEINHPFLIKLLWTGHDNRFLYMLMEFVPGGEL 131

  Fly   779 WTVMSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQ 843
            :|.:..|..|....:.|.|..:|.|.:||||...:||||||||::|..:|:.||.||||||  :.
Mouse   132 FTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGHIKLTDFGFAK--KL 194

  Fly   844 NEKTNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDV 908
            .::|.|..|||||:|||:|..:||.||||:||||||::|:|.|..||...|...|||:||:  ..
Mouse   195 VDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILA--CK 257

  Fly   909 IHMPSRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLK 973
            |..|.::..:::.|::.|.......|||..:.|..|||||.||..::|:.:..::|..||...|.
Mouse   258 IDFPRQLDFTSKDLIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRGVEWESVPQRKLKPPIVPKLS 322

  Fly   974 SWTDLQYFGPSGVENDYEPPEEL----SGWDKD 1002
            ...|:..|       :..|..||    |..|||
Mouse   323 GDGDISNF-------ETYPESELDKTPSVSDKD 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736
		CAP_ED	431..539	CDD:237999
		Crp	544..>650	CDD:223736
		CAP_ED	550..663	CDD:237999	2/11 (18%)
		S_TKc	695..951	CDD:214567	111/257 (43%)
		STKc_cGK	700..957	CDD:270724	110/258 (43%)
Prkx	NP_058675.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42		7/38 (18%)
		PTZ00263	31..355	CDD:140289	129/337 (38%)
		STKc_PRKX_like	44..335	CDD:270763	120/302 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	316..355		12/40 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910