Protein Alignment CG4839 and Prkar2b

DIOPT Version :10

• Sequence 1: NP_609349.1
• Gene: CG4839 / 34348
• FlyBaseID: FBgn0032187
• Length: 1003
• Species: Drosophila melanogaster
• Sequence 2: NP_035288.2
• Gene: Prkar2b / 19088
• MGIID: 97760
• Length: 416
• Species: Mus musculus
• Alignment Length: 323
• Identity: 92/323 - (28%)
• Similarity: 163/323 - (50%)
• Gaps: 23/323 - (7%)

  Fly   356 QQEIQQDATNSQDQMAGAEESHKSSDSSTPKTHR-VEGGLIYVRPNFPIQSDIEIES---IAKDE 416
            ::.::.|:.|.::     ||:.::...:.|..:| .....:......|.:.:.:.||   ..|.:
Mouse    78 EEPMRSDSENGEE-----EEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTD 137

  Fly   417 GTRNLIRTAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVI- 480
            ..||.::.|.:......|| |.|:...|::||.....::...:|.:.::|...||...|.:|:.
Mouse   138 DQRNRLQEACKDILLFKNL-DPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV 201

  Fly   481 ---RGGQLVASFGPATVFGELAILYNAPRQASIEAATDARVWKIARETFRAIMQISGSREREENL 542
               ..|:.|.::.....|||||::||.||.|:|.|.:...:|.:.|.|||.|:..:.:::|:...
Mouse   202 KCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYE 266

  Fly   543 QFLRSAPFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTV--TIKKLDEQQQ 605
            .|:.|.|||:..:.|..|||||::..|.|.....|:.:|:|.:.|:|:..|.|  |:|:..:.:.
Mouse   267 SFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEV 331

  Fly   606 EQ----IVANRKRGDYFGEQALLNADVRQASVYADAPGT-EVLMLDREAFISYLGTIKQLREK 663
            |:    .:|...||.||||.||:....|.||  |.|.|| :.|.:|.:||...||...::.::
Mouse   332 EENGAVEIARCFRGQYFGELALVTNKPRAAS--AHAIGTVKCLAMDVQAFERLLGPCMEIMKR 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	CAP_ED	431..539	CDD:237999	33/111 (30%)
		CAP_ED	550..663	CDD:237999	42/119 (35%)
		STKc_cGK	700..957	CDD:270724
Prkar2b	NP_035288.2	Dimerization and phosphorylation	1..151		13/77 (17%)
		DD_RIIbeta_PKA	3..45	CDD:438525
		CAP_ED	152..265	CDD:237999	34/113 (30%)
		CAP_ED	274..394	CDD:237999	42/121 (35%)