Protein Alignment CG4839 and Prkcd

DIOPT Version :10

• Sequence 1: NP_609349.1
• Gene: CG4839 / 34348
• FlyBaseID: FBgn0032187
• Length: 1003
• Species: Drosophila melanogaster
• Sequence 2: NP_579841.2
• Gene: Prkcd / 170538
• RGDID: 67383
• Length: 673
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 164/674 - (24%)
• Similarity: 291/674 - (43%)
• Gaps: 136/674 - (20%)

  Fly   383 STPKTHRVEGGLIYV---RPNFPIQSDIEI------ESIAKDEGTRNL-------------IRTA 425
            ||...|..||.:|.:   |......|::.:      |...|:.|....             ::..
  Rat    57 STFDAHIYEGRVIQIVLMRAAEDPMSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQYF 121

  Fly   426 IERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVIRGGQLVASFG 490
            :|..|...::..:|      .||.|...|:.::              .:.:...|:..:.:|:|
  Rat   122 LEDGDCKQSMRSEE------EAMFPTMNRRGAI--------------KQAKIHYIKNHEFIATF- 165

  Fly   491 PATVFGELAILYNAPRQASIEAATDARVWKIARETFRA---------------IMQISGSREREE 540
                ||:       |...|:   ....||.:.::.::.               |.:.:|:....
  Rat   166 ----FGQ-------PTFCSV---CKEFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNS- 215

  Fly   541 NLQFLRSAPFLQE---FDQSLLLKVVDLLQRKFYETDSC------IVREGELGNEFYIIRCGTVT 596
                 |...|.:|   .|.....||.:.:...|  .|.|      :|::|....:     ||...
  Rat   216 -----RDTIFQKERFNIDMPHRFKVYNYMSPTF--CDHCGSLLWGLVKQGLKCED-----CGMNV 268

  Fly   597 IKKLDEQQQEQIVANRKRGDYFGEQALLNADVRQASVYADAPGTEVLMLDREAFISYLGTIKQLR 661
            ..|..|:.......|:|   ...|  .||...::||...:.|.|             :|..:...
  Rat   269 HHKCREKVANLCGINQK---LLAE--ALNQVTQKASRKPETPET-------------VGIYQGFE 315

  Fly   662 EKPSSQRNDTSGRSST--KSLEFDNEYSQVAISELKKIATLGCGAFGRVDLVAY--NQQALALKI 722
            :|.:...||....:.|  |..|..|. .::.....:|:  ||.|:||:|.|...  .::..|:|.
  Rat   316 KKTAVSGNDIPDNNGTYGKIWEGSNR-CRLENFTFQKV--LGKGSFGKVLLAELKGKERYFAIKY 377

  Fly   723 IKKIEVVKQDQIEHVYNEKNVMIKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTVMSKRQY 787
            :||..|:..|.:|....||.|:....::||:..|..|::...:::|:||...|||:...:..:..
  Rat   378 LKKDVVLIDDDVECTMVEKRVLALAWENPFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGR 442

  Fly   788 FDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQN----EKTN 848
            |:...|.|.|..::....:||....||||||.:|:||..||:.|:.|||..|   :|    .:.:
  Rat   443 FELYRATFYAAEIICGLQFLHGKGIIYRDLKLDNVMLDKDGHIKIADFGMCK---ENIFGENRAS 504

  Fly   849 TFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHMPS 913
            ||.|||:|:||||:....:..:||:|:.|:|:||:|:|::||.|.::.::::.|  .:|..|.|.
  Rat   505 TFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESI--RVDTPHYPR 567

  Fly   914 RIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWTDL 978
            .|.|.::.::..|.::.||:|||.    ..:|:.|.:|::::|..|:.:::..|.|..:||.:|.
  Rat   568 WITKESKDIMEKLFERDPAKRLGV----TGNIRLHPFFKTINWNLLEKRKVEPPFKPKVKSPSDY 628

  Fly   979 QYFGPSGVENDYEPPEELSGWDKD 1002
            ..|.|..:.   |.| :||..||:
  Rat   629 SNFDPEFLN---EKP-QLSFSDKN 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	CAP_ED	431..539	CDD:237999	16/122 (13%)
		CAP_ED	550..663	CDD:237999	24/121 (20%)
		STKc_cGK	700..957	CDD:270724	87/262 (33%)
Prkcd	NP_579841.2	C1_nPKC_theta-like_rpt1	152..212	CDD:410384	11/74 (15%)
		C1_nPKC_theta-like_rpt2	231..280	CDD:410387	11/55 (20%)
		Protein Kinases, catalytic domain	351..666	CDD:473864	103/313 (33%)