DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4839 and LOC100498055

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	XP_002935815.2	Gene:	LOC100498055 / 100498055	-ID:	-	Length:	763	Species:	Xenopus tropicalis

Alignment Length:	807	Identity:	301/807 - (37%)
Similarity:	446/807 - (55%)	Gaps:	100/807 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   238 QQTDDTLSCQSSDANNNSAAKLTNGVV------------PQEQPER--EMGKQQALQAPPRAKSS 288
            ::.|..|..:..:.::.:.:||...|:            .||:.|:  ::.|:..::.....|..
Frog    16 KREDSCLFSRRREHSSGAFSKLQETVLLLEEELKQRWKELQEKDEKILQLEKELEVKVIQIDKLQ 80

  Fly   289 SNVSLNYLAKSQTDSQRRRRVSTMPDINIPPAPPLPPELLVPGTPLHLRKKRSMERQQQQKQQEQ 353
            ..:..|....|...||:::.:|.   ||..||                        |..:|..|.
Frog    81 DALGYNVTQTSPKGSQKKKLLSV---INQGPA------------------------QNNEKAAEA 118

  Fly   354 QQQQEIQQDATNSQDQMAGAEESHKSSDSSTPKTHRVEGGLIYVRPNFPIQSDIEIESIAKDEGT 418
            .::|:.                  |...|:.|.:..      |..|:   ..:.::..:.||...
Frog   119 HRRQKA------------------KEGVSAEPTSRH------YYNPS---SQNPDVTCVRKDSSA 156

  Fly   419 RNLIRTAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVIRGG 483
            :.||..||..||||..| :......:::.|....|.|..|:|:|...|:.:||.|:|..|||:..
Frog   157 KKLITGAIMSNDFLRQL-EASHVRCMVDCMYERVYSKSQLVIQEGAAGNHLYVLADGLLDVIQNS 220

  Fly   484 QLVASFGPATVFGELAILYNAPRQASIEAATDARVWKIARETFRAIMQISGSREREENLQFLRSA 548
            :|:....|.|.|||||||||..|.|:::|.||:::|.:.|:.|:.||..|...:.:|...||||.
Frog   221 RLLGQMHPGTAFGELAILYNCKRTATVKAVTDSKIWVLDRQVFQNIMMSSAQAQHQEYFSFLRSV 285

  Fly   549 PFLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTVTIKKLDEQQQE-QIVANR 612
            ..|::..:..|.|:||.|:..||:....|:||||.||.|:||..|.|.:.:..|..|| |.:...
Frog   286 SLLKDLPEEKLSKIVDCLEVDFYDKGDYIIREGEEGNTFFIIAKGKVCVTQAVEGSQEPQEIKTL 350

  Fly   613 KRGDYFGEQALLNADVRQASVYADAPGTEVLMLDREAFISYLGTIKQ----LRE------KPSSQ 667
            ..||||||:||::.|||.|::.|:...|:.|::||:.|...:||.::    |||      .....
Frog   351 GVGDYFGEKALISEDVRSANIIAEEDDTQCLVIDRDTFNQMVGTYQELQTYLREYVFQLALNDHD 415

  Fly   668 RNDTSGRSSTKSLEFDN-EYSQV--AISE---------LKKIATLGCGAFGRVDLVAYNQQ--AL 718
            |.:...:|...|:..|| |.:|:  .:|:         |..|.|||.|.||||:||....:  ..
Frog   416 RRNARRKSLHHSMSRDNSEVNQLRELVSKFSSTSPFRYLDVITTLGTGGFGRVELVKLKDEDMTF 480

  Fly   719 ALKIIKKIEVVKQDQIEHVYNEKNVM--IKCRQSPFIVQLYRTYRNDKYVYFLMEACMGGDVWTV 781
            |||.|||..:|...|.||||.|||::  |.|   .||::||||:|:.||||.|:|.|:||::|::
Frog   481 ALKCIKKKHIVDTHQQEHVYWEKNILQQINC---SFIIRLYRTFRDAKYVYMLLEVCLGGELWSI 542

  Fly   782 MSKRQYFDEKTAKFIAGCVVEAFDYLHSHHFIYRDLKPENLMLGTDGYCKLVDFGFAKFVRQNEK 846
            :.....|:|.||:|..|||:|||||||:...:|||||||||:|.::||.|:|||||||.:...:|
Frog   543 LRDTGPFEEGTARFCTGCVLEAFDYLHNRGIVYRDLKPENLLLDSEGYIKMVDFGFAKKIGPGKK 607

  Fly   847 TNTFAGTPEYVAPEIILDRGHDRAVDYWALGILVYELLVGKTPFRGVNQIKIYQQILSGIDVIHM 911
            |.||.|||||||||||::||||...|||:||||:||||.|..||.|.:.||||..:|.||:.:..
Frog   608 TWTFCGTPEYVAPEIIMNRGHDFGADYWSLGILIYELLTGSPPFSGTDPIKIYNMVLKGIEKVDF 672

  Fly   912 PSRIPKSAQHLVRHLCKQLPAERLGYQRKGIADIKRHSWFESLDWQRLKLKQLPSPIKRPLKSWT 976
            |.||.:.::.::|.||:..||||||.::.||:||::|.||:..:|:.|:.::|.||:||.:|..|
Frog   673 PHRIGRRSEDVIRRLCRINPAERLGNRKNGISDIRKHKWFQGFNWEGLRNRKLLSPLKREIKGIT 737

  Fly   977 DLQYFGPSGVENDYEPPEELSGWDKDF 1003
            |..||.....|:: |||:|||||||:|
Frog   738 DHSYFDNFLPESE-EPPDELSGWDKNF 763

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736	55/148 (37%)
		CAP_ED	431..539	CDD:237999	40/107 (37%)
		Crp	544..>650	CDD:223736	45/106 (42%)
		CAP_ED	550..663	CDD:237999	47/123 (38%)
		S_TKc	695..951	CDD:214567	138/259 (53%)
		STKc_cGK	700..957	CDD:270724	138/260 (53%)
LOC100498055	XP_002935815.2	CAP_ED	169..278	CDD:237999	40/109 (37%)
		CAP_ED	287..402	CDD:237999	44/114 (39%)
		STKc_cGK	460..719	CDD:270724	139/261 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123183at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X815
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920