DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4839 and prkar2a

DIOPT Version :9

Sequence 1:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster
Sequence 2:	XP_002933104.1	Gene:	prkar2a / 100486265	XenbaseID:	XB-GENE-982783	Length:	404	Species:	Xenopus tropicalis

Alignment Length:	380	Identity:	102/380 - (26%)
Similarity:	167/380 - (43%)	Gaps:	33/380 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 INIPPA-------------PPLPPELLVPGTPLHLRKKRSMERQQQQKQQEQQQQQEIQQDATNS 366
            |.|||.             ...||:|:........|.|....:........:...:.:..|....
Frog     3 IEIPPGLTDLLQGYTVEVLRQKPPDLVEFAIQYFTRLKEKQLQDGAGAGSLRPHARVVNFDGEPM 67

  Fly   367 QDQMAGAEESHK----SSDSSTPKTHRVEGGL-IYVRPNFPIQSDIEIESIA---KDEGTRNLIR 423
            |.:..|.||..:    .||...|..:|....: :......|.:.|.:.|...   |.:..|..::
Frog    68 QTESNGDEEEDEEDDDDSDFEPPVINRYSRRVSVCAEAYNPDEEDEDTEPRVVRPKTDEQRCRLQ 132

  Fly   424 TAIERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVI--RGGQ-- 484
            .|.:......|| |:|:...|::||.....:....:|.:.::|...||...||||:.  |.||
Frog   133 EACKDILLFKNL-DQEQLSQVLDAMFEMRVKPQEHVIDQGDDGDNFYVVERGQYDIFVERDGQSR 196

  Fly   485 LVASFGPATVFGELAILYNAPRQASIEAATDARVWKIARETFRAIMQISGSREREENLQFLRSAP 549
            .|..:.....|||||::||.||.|:|.|.::..:|.:.|.|||.|:..:.:::|:....|:.|.|
Frog   197 CVGRYDNHGSFGELALMYNTPRAATIVATSEGALWGLDRVTFRRIILKNNAKKRKTYEIFIESVP 261

  Fly   550 FLQEFDQSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTVTI------KKLDEQQQEQI 608
            .|:..:.|..:|:||::..:.|:....|:.:|:..:.|:|:..|.|.|      |...|..||..
Frog   262 VLKFLELSERMKIVDVIAARVYKDGDRIIAQGDKADCFFIVESGEVKIMMKSKTKTGQESNQEVE 326

  Fly   609 VANRKRGDYFGEQALLNADVRQASVYADAPGTEVLMLDREAFISYLGTIKQLREK 663
            :|..|.|.||||.||:....|.||.|| ....:.|::|.:||...||....:.::
Frog   327 IARCKSGQYFGELALVTNKPRAASAYA-VGDVKCLIMDVQAFERLLGPCMDIMKR 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4839	NP_609349.1	Crp	428..577	CDD:223736	47/152 (31%)
		CAP_ED	431..539	CDD:237999	37/111 (33%)
		Crp	544..>650	CDD:223736	36/111 (32%)
		CAP_ED	550..663	CDD:237999	37/118 (31%)
		S_TKc	695..951	CDD:214567
		STKc_cGK	700..957	CDD:270724
prkar2a	XP_002933104.1	DD_RIIalpha_PKA	3..43	CDD:213050	9/39 (23%)
		CAP_ED	140..253	CDD:237999	38/113 (34%)
		CAP_ED	262..382	CDD:237999	37/120 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910