Protein Alignment CG13133 and CRYAB

DIOPT Version :10

• Sequence 1: NP_609343.1
• Gene: CG13133 / 34342
• FlyBaseID: FBgn0032181
• Length: 217
• Species: Drosophila melanogaster
• Sequence 2: NP_001876.1
• Gene: CRYAB / 1410
• HGNCID: 2389
• Length: 175
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 63/318 - (19%)
• Similarity: 95/318 - (29%)
• Gaps: 143/318 - (44%)

  Fly   262 RSEQEDKKDYVQSY--VDTLL-------------DLELPEENRKLNE-----------EDIMNLC 300
            |:.:..||:...||  :|:.|             |..:|.|...:.|           ..:..|.
Human    61 RNVERLKKELRASYCLIDSFLGNSELIGDLTQCVDCVIPPEGSVMQETLSGFAEATGTAFVSLLV 125

  Fly   301 SEFLTAGTD-------TTATALQWIMANLV-----KYPEIQERLHEEIKSVVGEEAKEVEEEDVE 353
            |..:.|.||       ..|..|.|::.:|.     .||
Human   126 SGRVVAATDGWWRLGMPEAVLLPWLVGSLPPQAARDYP--------------------------- 163

  Fly   354 KMPYLKAVVLEGLRRHPPGHFLLPHSVTEDTVLGGYKV-------PKNGTINFMVAEIGRDPVEW 411
              .||           |.|...:||.:...|:|.|.::       |..|.::..:.|      .|
Human   164 --VYL-----------PHGSPTVPHRLLTLTLLRGLELCLLCGPRPPLGELDPQLLE------RW 209

  Fly   412 EEPMAFKPERFMGEEEAVDLTGSRGIKMMPFGAGRRICPG-------IGLAMLHLE-----YYV- 463
            .:|: .:|.|                ..:|.|. |.:..|       :||.:||||     :.|
Human   210 WQPL-LEPLR----------------ACLPLGP-RALPDGFPLHSDILGLLLLHLELRRCLFTVE 256

  Fly   464 ------------ANMVREFQWKEVQGH---EVDLTEKLEFTVVMKHPLKALAVPRRCH 506
                        ..::|.|.......|   |....||.|.||   ||.:   .||.|:
Human   257 PSKDKEPSPEQRRRLLRNFYTLVATTHFPPEPGPAEKQEDTV---HPAQ---TPRACY 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13133	NP_609343.1	metazoan_ACD	87..163	CDD:107247
CRYAB	NP_001876.1	Crystallin	1..55	CDD:425732
		ACD_alphaB-crystallin_HspB5	67..150	CDD:107246	17/82 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	146..175		9/68 (13%)