DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn31A and Serpinb6c

DIOPT Version :9

Sequence 1:NP_609341.1 Gene:Spn31A / 34339 FlyBaseID:FBgn0032178 Length:382 Species:Drosophila melanogaster
Sequence 2:NP_001369781.1 Gene:Serpinb6c / 97848 MGIID:2145481 Length:379 Species:Mus musculus


Alignment Length:355 Identity:95/355 - (26%)
Similarity:167/355 - (47%) Gaps:32/355 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 QNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRL-KQRFASNAKMANFYAAELGNIT-TDADTF 91
            :||.:||:.:.:.|.::.||:.|.||.::.:.|.| |...:.:..:...:...|..:. |.....
Mouse    26 KNVFLSPISISSALVMVLLGAKGTTAIQITQALSLGKCSSSEDGDVHQGFQLLLSEVNKTGTQYS 90

  Fly    92 LQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLE-QTEKLRRHISEQILASVGGGSWKDIHV 155
            |:..|||.......:...|:.....::.|..|.:|.: .||:.|:||:..: |.......|::..
Mouse    91 LKAANRLFGEKTFDILASFKDSCHKFYEAEMEELDFKGATEQSRQHINTWV-AKKTEDKIKELLS 154

  Fly   156 AGGSSANT-LLLLLAANLQSKWFLPFSAYRTGLYEFH-SGSQVKSVPMLFDDDMFVKFAELRDLD 218
            .|...:|| |:|:.|...:.||...|:...|....|. |.::.|.|.|:|....| |...:.::.
Mouse   155 PGTIHSNTPLILVNAVYFKGKWEKQFNKEDTREMPFKVSKNEEKPVQMMFQKSTF-KMTYVEEIS 218

  Fly   219 ARAIELPYEHAEELSMLLILPNQRGGLQELEKQL-HD-------LDLGALQQRMQMEGVQVLLPK 275
            .:.:.|||. ..||:|:::||::...|..:||:: |:       ||      ||:.|.|:|.||.
Mouse   219 TKILLLPYV-GNELNMIIMLPDEHVELSTVEKEITHEKFIEWTRLD------RMKGEKVEVFLPW 276

  Fly   276 FSIDFECSLRQPLKQLGFEEIF-AASANFKHLHASANLPIADVLQKLRINLNESGSGSGPELPKN 339
            |.::....::..|.:||..:.| ...|:|..:.:...|.:::|:.|..:.:||.||        .
Mouse   277 FKLEENYDMKDVLCKLGMTDAFEEGRADFSGISSKQGLFLSNVIHKSVVEVNEEGS--------E 333

  Fly   340 ATEYKPIVISNSSRQ-KFFRADHPFFFAIR 368
            ||....||:..|||. ..|..:.||.|.|:
Mouse   334 ATAATTIVLKGSSRSTPCFCVNRPFIFFIQ 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn31ANP_609341.1 SERPIN 18..379 CDD:238101 95/355 (27%)
Serpinb6cNP_001369781.1 serpin 2..379 CDD:422956 95/355 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG57242
OrthoDB 1 1.010 - - D556621at33208
OrthoFinder 1 1.000 - - FOG0000050
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.930

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