Protein Alignment Spn31A and Serpina12

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 381
• Identity: 88/381 - (23%)
• Similarity: 163/381 - (42%)
• Gaps: 60/381 - (15%)

  Fly    10 YDCHIGAGIYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMA 74
            ::...|..:...:|::..:.|:.:|||.:....|:|.||:..:|.||:::....|:....:...|
Mouse    51 HNMEFGFKLLQRLASNSPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFKEMSNWDVHAA 115

  Fly    75 NFYAAELGNITTDADTFLQLQNRLMLSSESGVADDFQKIAQTYFHA---TAECVDLEQTEK-LRR 135
            ..|.....|..|: ||.:.|.|.|.:..:......|..:|:..:.|   .....|||.|:| :.|
Mouse   116 FHYLLHKLNQETE-DTKMNLGNALFMDQKLRPQQRFLNLAKNVYDADMVLTNFQDLENTQKDINR 179

  Fly   136 HISEQ-------ILASVGGGSWKDIHVAGGSSANTLLLLLAANLQSKWFLPFSAYRTGLYEF--H 191
            :||::       ::.|:..|:             .::|......:.:|...|...:|...||  .
Mouse   180 YISQKTHSRIKNMVKSIDPGT-------------VMILTNYIYFRGRWQYEFDPKQTKEEEFFIE 231

  Fly   192 SGSQVKSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQLHDLD 256
            .|..|| |||:|...:: ..|....|....:|:||.  ..::...:||: .|.|:.||:.| ..|
Mouse   232 KGKTVK-VPMMFQRGLY-DMAYDSQLSCTILEIPYR--GNITATFVLPD-NGKLKLLEQGL-QAD 290

  Fly   257 LGA-----LQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASANLPIAD 316
            :.|     |.:|:    |.|.:||..|....::::.|.:||..:||..:.:...:.:..:|.:.:
Mouse   291 IFAKWKSLLSKRV----VDVWVPKLRISSTYNMKKVLSRLGISKIFEENGDLTRISSHRSLKVGE 351

  Fly   317 VLQKLRINLNESG----SGSGPE-LPKNATEYKPIVISNSSRQKFFRADHPFFFAI 367
            .:.|..:.::|.|    :|||.: ||.....:             .:.|.||...|
Mouse   352 AVHKAELKMDEKGMEGAAGSGAQTLPMETPRH-------------MKLDRPFLMMI 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	88/381 (23%)
Serpina12	NP_080811.1	serpinA12_vaspin	40..411	CDD:381026	88/381 (23%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		6/17 (35%)