Protein Alignment Spn31A and Serpinb1a

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_079705.2
• Gene: Serpinb1a / 66222
• MGIID: 1913472
• Length: 379
• Species: Mus musculus
• Alignment Length: 377
• Identity: 98/377 - (25%)
• Similarity: 172/377 - (45%)
• Gaps: 37/377 - (9%)

  Fly    18 IYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLR------LKQRFAS-NAKMAN 75
            ::.::..|....|:..||..:.:.|:::.||:.|:||.:|.|...      :..||.| ||:::.
Mouse    15 LFQTLNESSPTGNIFFSPFSISSALAMVILGAKGSTAAQLSKTFHFDSVEDIHSRFQSLNAEVSK 79

  Fly    76 FYAAELGNITTDADTFLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVD-LEQTEKLRRHISE 139
                      ..|...|:|.|||..........::....|..:.|....|| |..:|..|:.|::
Mouse    80 ----------RGASHTLKLANRLYGEKTYNFLPEYLASTQKMYGADLAPVDFLHASEDARKEINQ 134

  Fly   140 QILASVGGGSWKDIHVAGGSSANTLLLLLAANLQSKWFLPFSAYRTGLYEFH-SGSQVKSVPMLF 203
            .:.....|...:.:.|....|...|:|:.|...:..|...|....|....|. |....|:|.|::
Mouse   135 WVKGQTEGKIPELLSVGVVDSMTKLVLVNAIYFKGMWEEKFMTEDTTDAPFRLSKKDTKTVKMMY 199

  Fly   204 DDDMFVKFAELRDLDARAIELPYEHAEELSMLLILP----NQRGGLQELEKQ--LHDLDLGALQQ 262
            ....| .|..:.||..:.:|:||: ..||||:::||    ::..||:::|||  |..|.....::
Mouse   200 QKKKF-PFGYISDLKCKVLEMPYQ-GGELSMVILLPKDIEDESTGLKKIEKQITLEKLLEWTKRE 262

  Fly   263 RMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAAS-ANFKHLHASANLPIADVLQKLRINLN 326
            .::...|.|.||:|.|:...:|...|.:||.:::|::| |:...:..|.:|.|:.::.|..:.:|
Mouse   263 NLEFIDVHVKLPRFKIEESYTLNSNLGRLGVQDLFSSSKADLSGMSGSRDLFISKIVHKSFVEVN 327

  Fly   327 ESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFAIR---SENVTYL 375
            |.|:.:.......||      ......::.|..||||.|.||   :.||.:|
Mouse   328 EEGTEAAAATGGIAT------FCMLLPEEEFTVDHPFIFFIRHNPTSNVLFL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	98/377 (26%)
Serpinb1a	NP_079705.2	serpinB1_LEI	1..379	CDD:381028	98/377 (26%)
		CARD-binding motif (CBM). /evidence=ECO:0000250|UniProtKB:P30740	351..379		11/23 (48%)