Protein Alignment Spn31A and SERPINB4

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_002965.1
• Gene: SERPINB4 / 6318
• HGNCID: 10570
• Length: 390
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 100/404 - (24%)
• Similarity: 176/404 - (43%)
• Gaps: 53/404 - (13%)

  Fly     1 MSEAANPTPYDCHIGAGIYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQ 65
            :|||.....:|      ::.....| .|.|:..||:.:.:.|.::.||:...||:::.|.|...|
Human     4 LSEANTKFMFD------LFQQFRKS-KENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQ 61

  Fly    66 RFASNA-KMANFYAAELGNI-------------TTDADTFLQLQNRLMLSSESGVADDFQKIAQT 116
            ...:.. |.|.::....||:             :|||.. |::.|:|..........::....:.
Human    62 VTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYE-LKIANKLFGEKTYQFLQEYLDAIKK 125

  Fly   117 YFHATAECVDLEQT-EKLRRHISEQILASVGGGSWKDIHV--------AGGSSAN--TLLLLLAA 170
            ::..:.|..|.... |:.|:.|:          ||.:...        ..|:..|  ||:|:.|.
Human   126 FYQTSVESTDFANAPEESRKKIN----------SWVESQTNEKIKNLFPDGTIGNDTTLVLVNAI 180

  Fly   171 NLQSKWFLPFSAYRTGLYEFHSGSQV-KSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSM 234
            ..:.:|...|....|...:|...... |||.|:...:.| .||.|.|:.|:.:|:||: .::|||
Human   181 YFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSF-NFALLEDVQAKVLEIPYK-GKDLSM 243

  Fly   235 LLILPNQRGGLQELEKQL--HDLDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIF 297
            :::|||:..|||:||::|  ..|......|.|:...|.:.||:|.::....|:..|:.:|...||
Human   244 IVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIF 308

  Fly   298 AASANFKHLHASANLPIADVLQKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHP 362
            ...|:...:..|..|.::.||.|..:.:.|.|..:..     ||....:.:|:.|..:.|..:||
Human   309 NGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAA-----ATAVVVVELSSPSTNEEFCCNHP 368

  Fly   363 FFFAIRSENVTYLM 376
            |.|.||......::
Human   369 FLFFIRQNKTNSIL 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	97/395 (25%)
SERPINB4	NP_002965.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	100/404 (25%)