DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn31A and serpinb14

DIOPT Version :9

Sequence 1:	NP_609341.1	Gene:	Spn31A / 34339	FlyBaseID:	FBgn0032178	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_002665111.3	Gene:	serpinb14 / 569051	ZFINID:	ZDB-GENE-050506-148	Length:	437	Species:	Danio rerio

Alignment Length:	430	Identity:	106/430 - (24%)
Similarity:	178/430 - (41%)	Gaps:	102/430 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEEL--------------------QKQLR 62
            ::..|:...|..||..||:.:.:.|:::.||:.|.||:::                    |..::
Zfish    15 LFKKISGGNASGNVFYSPVSISSALAMVSLGAKGNTADQMFKVLGFNNLPKSAGATPEAHQSMMQ 79

  Fly    63 LKQRFASNAK-----------------------------------MANF--YAAELGNITTDADT 90
            ..|:..|..|                                   .:||  :.:||..  ..|..
Zfish    80 QAQKPKSGVKDQHGQAMMQQTQKIDIPAELKKGSAVPGQKAEEQIHSNFNKFMSELNK--PGAPY 142

  Fly    91 FLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLRRHISEQILASVGGGSW----- 150
            .|.|.|||.........:.|...|:.|:.|..|.||.:...:..|         |...:|
Zfish   143 VLSLANRLYGEQTYQFVEKFLSDAKRYYEAGLEKVDFKNKSEAAR---------VNINTWVEKNT 198

  Fly   151 ----KDIHVAGGSSANTLLLLLAA-----NLQSKWFLPFSAYRTGLYEFHSGSQVKSVPMLFDDD 206
                ||:..:|...|.|.|:|:.|     |.:.|:  |..|...|.::.:. :|.|.|.|::...
Zfish   199 QEKIKDLLPSGAIDAMTRLVLVNAIYFKGNWERKF--PKEATNDGQFKLNK-NQTKPVKMMYQKA 260

  Fly   207 MFVKFAELRDLDARAIELPYEHAEELSMLLILPNQ----RGGLQELEKQL--HDLDLGALQQRMQ 265
            .| ..|.:.:::::.:||||. .:.||||:|||:|    ..||::|||.|  ..|......:.|:
Zfish   261 HF-PLASIPEMNSQVLELPYV-GKNLSMLIILPDQIEDATTGLEKLEKALTYEKLMEWTKPEVMR 323

  Fly   266 MEGVQVLLPKFSIDFECSLRQPLKQLGFEEIF-AASANFKHLHASANLPIADVLQKLRINLNESG 329
            .:.|||.||||.::....::..|..:|.|::| ....|...:.:|.:|.::.|:.|..:.:||.|
Zfish   324 QQEVQVSLPKFKMEQTYDMKSLLVSMGMEDVFDPQKVNLTGMSSSNDLVLSKVIHKAFVEVNEEG 388

  Fly   330 SGSGPELPKNATEYKPIVISNSSR-QKFFRADHPFFFAIR 368
            :       :.|.....|::....| .:.|.|||||.|.||
Zfish   389 T-------EAAAATGAIMMLRCIRLPQSFNADHPFLFFIR 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	106/430 (25%)
serpinb14	XP_002665111.3	SERPIN	4..437	CDD:294093	106/430 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.930