Protein Alignment Spn31A and SERPINB10

DIOPT Version :9

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_005015.1
• Gene: SERPINB10 / 5273
• HGNCID: 8942
• Length: 397
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 92/400 - (23%)
• Similarity: 176/400 - (44%)
• Gaps: 74/400 - (18%)

  Fly    22 IATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEEL------------------QKQLRLKQRFA 68
            :|.|...:|:..|...:..:|::::||:.|.||.::                  :|:.:::...:
Human    19 LAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQGVKCDPESEKKRKMEFNLS 83

  Fly    69 SNAKMANFYAAELGNITTDADTFLQLQNRLMLSSESGVA--DDFQKIAQTYFHATAECVD-LEQT 130
            ::.::.:.:...:..|....|.:| |:....:..|...|  :.:.:..:|||.|..:.|: :|.:
Human    84 NSEEIHSDFQTLISEILKPNDDYL-LKTANAIYGEKTYAFHNKYLEDMKTYFGAEPQPVNFVEAS 147

  Fly   131 EKLRRHISEQILASVGGGSWKDIHVAGG----------SSANTLLLLLAANLQSKWFLPFSAYRT 185
            :::|:.|:          ||.:....|.          .|...::|:.|...:..|...|....|
Human   148 DQIRKDIN----------SWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNT 202

  Fly   186 GLYEFHSGSQVKSVPMLFDDDMFVKFAELRDLDARAIELP-------YEHAEELSMLLILPNQRG 243
            ....|.. ::..|.|:..   ||:|    :.|....||.|       |..:.:||:|::||....
Human   203 TEKPFRI-NETTSKPVQM---MFMK----KKLHIFHIEKPKAVGLQLYYKSRDLSLLILLPEDIN 259

  Fly   244 GLQELEKQL--HDLDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAAS-ANFKH 305
            ||::|||.:  ..|:.......|::..||:.||||.::....|:..|..:|..:.|:.| |:|..
Human   260 GLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSG 324

  Fly   306 LHASANLPIADVLQKLRINLNESG----SGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFA 366
            :.::.||.:::|..|..:.:||.|    :|||.|:        .|.|...|.:  |.|:|||.|.
Human   325 MSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEI--------DIRIRVPSIE--FNANHPFLFF 379

  Fly   367 IRSENVTYLM 376
            ||......::
Human   380 IRHNKTNTIL 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	92/399 (23%)
SERPINB10	NP_005015.1	PAI-2	4..397	CDD:239013	92/399 (23%)
		Nuclear localization signal	74..77		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930