Protein Alignment Spn31A and SERPINB8

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_002631.3
• Gene: SERPINB8 / 5271
• HGNCID: 8952
• Length: 374
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 98/358 - (27%)
• Similarity: 170/358 - (47%)
• Gaps: 27/358 - (7%)

  Fly    29 QNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMANFYAAELGNIT-TDADTFL 92
            :||..||:.:.:.|:::|:|:.|:||.::.:.|.|.:    :..:...:.:.|..:. |.....|
Human    26 RNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYK----DGDIHRGFQSLLSEVNRTGTQYLL 86

  Fly    93 QLQNRLMLSSESGVADDFQKIAQTYFHATAECVDL-EQTEKLRRHISEQILASVGGGSWKDIHVA 156
            :..|||..........||::..|.::.|..|.:.. |.||:.|:||::.: |....|...::..|
Human    87 RTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWV-AEKTEGKISEVLDA 150

  Fly   157 GGSSANTLLLLL-AANLQSKWFLPFS-AYRTGLYEFHSGSQVKSVPMLFDDDMFVKFAELRDLDA 219
            |.....|.|:|: |...:.||...|. .|..|:. |.:..:.|:|.|:|.:..| |.....::..
Human   151 GTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGML-FKTNEEKKTVQMMFKEAKF-KMGYADEVHT 213

  Fly   220 RAIELPYEHAEELSMLLILPNQRGGLQELEKQL--HDLDLGALQQRMQMEGVQVLLPKFSIDFEC 282
            :.:||||.. |||||:::||:....|..:||.|  .........:::....|||.||:..::...
Human   214 QVLELPYVE-EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESY 277

  Fly   283 SLRQPLKQLGFEEIF-AASANFKHLHASANLPIADVLQKLRINLNESGSGSGPELPKNATEYKPI 346
            .|...|::||..:.| .|.|:|..:....|:|::.|..|..:.:||.|:.:..     ||    .
Human   278 DLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAA-----AT----A 333

  Fly   347 VISNSSRQKF---FRADHPFFFAIRSENVTYLM 376
            |:.||...:.   |.|||||.|.||......::
Human   334 VVRNSRCSRMEPRFCADHPFLFFIRHHKTNCIL 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	98/358 (27%)
SERPINB8	NP_002631.3	serpinB8_CAP-2	1..374	CDD:381033	98/358 (27%)