Protein Alignment Spn31A and SERPINE2

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: XP_005246698.1
• Gene: SERPINE2 / 5270
• HGNCID: 8951
• Length: 410
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 103/389 - (26%)
• Similarity: 164/389 - (42%)
• Gaps: 52/389 - (13%)

  Fly    15 GAGIYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNA-----KMA 74
            |..:::.|..|....|:|:||..:.:.|.:|.||:||.|    :|||.:..|:..|.     |..
Human    47 GIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRT----KKQLAMVMRYGVNGVGKILKKI 107

  Fly    75 NFYAAELGN---ITTDADTFLQLQNRLMLSSESGVADDFQ-KIAQTYFHATAECVDL-------E 128
            |.......|   :|.....|::..:.:.:...:...|.|| ::....|...|...|.       |
Human   108 NKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNE 172

  Fly   129 QTEKLRRHISEQILASVGGGSWKDIHVAGGSSANTLLLLLAANLQSKWFLPFSAYRTGLYEF-HS 192
            ..:.:...:|..::..|               ...|:|:.|...:..|...|....|....| .:
Human   173 TRDMIDNLLSPDLIDGV---------------LTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAA 222

  Fly   193 GSQVKSVPMLFDDDMF--VKFAELRDLDARAIELPYEHAEELSMLLILPNQRG-GLQELEKQLHD 254
            ..:...||||....:|  ...:...||....||||| |.|.:|||:.||.:.. .|..:...:..
Human   223 DGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPY-HGESISMLIALPTESSTPLSAIIPHIST 286

  Fly   255 LDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAAS-ANF-KHLHASANLPIADV 317
            ..:.:....|..:.|||:||||:...:..|::|||.||..::|.:| ||| |....|.||.::.:
Human   287 KTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHI 351

  Fly   318 LQKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFAIRSE--NVTYLMGHV 379
            |||.:|.::|.|:       |.:.....|:|:.|| ..:|..|.||.|.||..  .....||.:
Human   352 LQKAKIEVSEDGT-------KASAATTAILIARSS-PPWFIVDRPFLFFIRHNPTGAVLFMGQI 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	103/389 (26%)
SERPINE2	XP_005246698.1	serpinE2_GDN	33..408	CDD:381039	103/389 (26%)