Protein Alignment Spn31A and SERPINB5

DIOPT Version :9

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_002630.2
• Gene: SERPINB5 / 5268
• HGNCID: 8949
• Length: 375
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 91/377 - (24%)
• Similarity: 171/377 - (45%)
• Gaps: 67/377 - (17%)

  Fly    30 NVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLK---------QRFASNA-KMANFYAAELGNI 84
            ||:.||:.|..:|||..:|:.|.||.|:.:.|..:         |...|:. |:::||:
Human    27 NVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYS------ 85

  Fly    85 TTDADTFLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDL-EQTEKLRRHISEQILASVGGG 148
                   |:|..||.:.....::.:|....:..:....|.||. ::.|:.:..|:..|
Human    86 -------LKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSI------- 136

  Fly   149 SWKDI------HVAGGSSAN---TLLLLLAANLQSKWFLPFSAYRTGLYEFH-SGSQVKSVPMLF 203
              ||:      ::...:|.|   .:|::.||....||...||...|....|. :.:..|.|.|:.
Human   137 --KDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMN 199

  Fly   204 DDDMFVKFAELRDLDARAIELPYEHAEELSMLLILP----NQRGGLQELEKQLHDLDLGALQQRM 264
            .:..|. ...:..::.:.||||::: :.|||.::||    ::..||:::||||:...|.......
Human   200 MEATFC-MGNIDSINCKIIELPFQN-KHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPS 262

  Fly   265 QMEGVQVLL--PKFSIDFECSLRQPLKQLGFEEIFAA-SANFKHLHASANLPIADVLQKLRINLN 326
            .|...:|.|  |||.::.....:..|:.||.:.||:. :::|..:..:..:.:::|:.|:.:.:.
Human   263 TMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEIT 327

  Fly   327 ESGSGSGPELP-KNATEYKPIVISNSSRQKFFRADHPFFFAIR---SENVTY 374
            |.| |...|:| ....::|..:          .|||||.:.||   :.|:.:
Human   328 EDG-GDSIEVPGARILQHKDEL----------NADHPFIYIIRHNKTRNIIF 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	91/377 (24%)
SERPINB5	NP_002630.2	maspin_like	4..375	CDD:239012	91/377 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930