Protein Alignment Spn31A and SERPINA4

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 85/395 - (21%)
• Similarity: 169/395 - (42%)
• Gaps: 46/395 - (11%)

  Fly     9 PYDCHIGAGIYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKM 73
            |.:.......|:.||:....:|:..|||.:.|..::|.||:...:..::.:.|.......|.:.:
Human    90 PANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDV 154

  Fly    74 ANFYAAELGNIT-------TDADTFLQLQNRL-----MLSSESGVADDFQKIAQTYFHATAECVD 126
            ...:...|..:.       |...:.|.|.:.|     .|:....|.:  .|:..|.|:.|...:.
Human   155 HRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE--AKLFHTNFYDTVGTIQ 217

  Fly   127 LEQTEKLRRHISEQILASVGGGSWKDIHVAGGSSANTLLLLL-AANLQSKWFLPFSAYRTGLYEF 190
            |     :..|:.::....:       :.:......:.|::|: ....::.|..||.:.||...:|
Human   218 L-----INDHVKKETRGKI-------VDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDF 270

  Fly   191 H--SGSQVKSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQLH 253
            :  ..:.|: |||:..|.....:...|.|....:.:.|:  .:.::..||||| |.::|:|:.|.
Human   271 YVDENTTVR-VPMMLQDQEHHWYLHDRYLPCSVLRMDYK--GDATVFFILPNQ-GKMREIEEVLT 331

  Fly   254 DLDL----GALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASANLPI 314
            ...|    ..|::|...:.:::.||||||.....|.|.|.:|||.::|:..|:...:.....|..
Human   332 PEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEA 396

  Fly   315 ADVLQKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPF---FFAIRSENVTYLM 376
            :....|..::::|:|:.:..     ||.:.....|..:.:...|.:.||   .|:..:::|.:|
Human   397 SKSFHKATLDVDEAGTEAAA-----ATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFL- 455

  Fly   377 GHVVE 381
            |.||:
Human   456 GKVVD 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	84/394 (21%)
SERPINA4	NP_001275961.1	serpinA4_KST	81..463	CDD:381020	85/395 (22%)