Protein Alignment Spn31A and SERPINA1

DIOPT Version :9

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 94/383 - (24%)
• Similarity: 161/383 - (42%)
• Gaps: 30/383 - (7%)

  Fly     8 TPYDCHIGAGIYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAK 72
            ||........:|..:|......|:..||:.:....::|.||:...|.:|:.:.|.........|:
Human    51 TPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115

  Fly    73 MANFYAAELGNITTDADTFLQLQ--NRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLRR 135
            :...: .||.......|:.|||.  |.|.||....:.|.|.:..:..:|:.|..|:...||:.::
Human   116 IHEGF-QELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179

  Fly   136 HISEQILASVGGGSWKDIHVAGGSSANTLLLLLAAN---LQSKWFLPFSAYRTGLYEFHSGSQVK 197
            .|::.:.....|   |.:.:......:|:..|:  |   .:.||..||....|...:||. .||.
Human   180 QINDYVEKGTQG---KIVDLVKELDRDTVFALV--NYIFFKGKWERPFEVKDTEEEDFHV-DQVT 238

  Fly   198 S--VPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQL-HDLDLGA 259
            :  |||:....|| .....:.|.:..:.:.|  ....:.:..||:: |.||.||.:| ||:....
Human   239 TVKVPMMKRLGMF-NIQHCKKLSSWVLLMKY--LGNATAIFFLPDE-GKLQHLENELTHDIITKF 299

  Fly   260 LQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASANLPIADVLQKLRIN 324
            |:.. ......:.|||.||.....|:..|.|||..::|:..|:...:...|.|.::..:.|..:.
Human   300 LENE-DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLT 363

  Fly   325 LNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFAIRSENV--TYLMGHVV 380
            ::|.|:.:.     .|...:.|.:|.....||   :.||.|.:..:|.  ...||.||
Human   364 IDEKGTEAA-----GAMFLEAIPMSIPPEVKF---NKPFVFLMIEQNTKSPLFMGKVV 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	90/370 (24%)
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	90/376 (24%)
		RCL	368..392		6/31 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010