Protein Alignment Spn31A and SERPINA10

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: XP_016876842.1
• Gene: SERPINA10 / 51156
• HGNCID: 15996
• Length: 484
• Species: Homo sapiens
• Alignment Length: 383
• Identity: 93/383 - (24%)
• Similarity: 162/383 - (42%)
• Gaps: 72/383 - (18%)

  Fly    30 NVVVSPLLLEATLSLLFLGSDGATAEELQKQLR------------------LKQRFASNAKMANF 76
            |:|.||..:...::.|.||:.|.|..::::.|.                  |::..:.|
Human   137 NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRN------ 195

  Fly    77 YAAELGNITTDADTFLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDL-----EQTEKLRRH 136
              .||| :|..:..|:.        .:..|.:.|..:::.||  ..|||.:     .|.::|..|
Human   196 --LELG-LTQGSFAFIH--------KDFDVKETFFNLSKRYF--DTECVPMNFRNASQAKRLMNH 247

  Fly   137 -ISEQILASVGGGSWKDIHVAGGSSANTLLLLLAANL-QSKWFLPFSAYRTGLYEFHSGS-QVKS 198
             |:::....:.       .:....:..|.|:|:...| :.||..||....|.:..||... :...
Human   248 YINKETRGKIP-------KLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIK 305

  Fly   199 VPMLFDDDMFVKFAELRDLDAR--AIELPYEHAEELSMLLILPNQRGGLQELEKQLHDLDLGALQ 261
            |||::...   |||...|.:.|  .::|||:  ...:||::|..:.|....||..|....:....
Human   306 VPMMYGAG---KFASTFDKNFRCHVLKLPYQ--GNATMLVVLMEKMGDHLALEDYLTTDLVETWL 365

  Fly   262 QRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASA-NLPIADVLQKLRINL 325
            :.|:...::|..|||.:|.:..:.:.|:|:|...||:..|:...|.|:. ||.::.|||:..|.:
Human   366 RNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEV 430

  Fly   326 NESGSGSGPELPKNATEYK-PIVISNSSRQKFFRADHPFFFAIRSE--NVTYLMGHVV 380
            :|.|:.:...:....|.|. |.||         :.|.||.|.|..|  .:...:|.||
Human   431 DERGTEAVAGILSEITAYSMPPVI---------KVDRPFHFMIYEETSGMLLFLGRVV 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	93/383 (24%)
SERPINA10	XP_016876842.1	serpinA10_PZI	107..482	CDD:381011	93/383 (24%)