Protein Alignment Spn31A and SERPINA5

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_000615.3
• Gene: SERPINA5 / 5104
• HGNCID: 8723
• Length: 406
• Species: Homo sapiens
• Alignment Length: 382
• Identity: 86/382 - (22%)
• Similarity: 176/382 - (46%)
• Gaps: 31/382 - (8%)

  Fly    11 DCHIGA------------GIYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRL 63
            |.|:||            .:|.::|::...|::..||:.:..:|::|.||:..:|..::.:.|.|
Human    33 DLHVGATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGL 97

  Fly    64 KQRFASNAKMANFYAAELGNITTDADTF-LQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDL 127
            ..:.:|..::...:...|..:....|.| |.|.|.|.......:.|.|....:|.:.|.....:.
Human    98 NLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF 162

  Fly   128 EQTEKLRRHISEQILASVGGGSWKDIHVAGGSSANTLLLLLAAN---LQSKWFLPFSAYRTGLYE 189
            ..:....:.|::.:.....|   |.:.:.....:|.:::::  |   .::||...|:...|...:
Human   163 RDSAGAMKQINDYVAKQTKG---KIVDLLKNLDSNAVVIMV--NYIFFKAKWETSFNHKGTQEQD 222

  Fly   190 FHSGSQ-VKSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQLH 253
            |:..|: |..|||:..:|.:....: |:|..|.:.:||:  ...:.|.|||:: |.:|::|..|.
Human   223 FYVTSETVVRVPMMSREDQYHYLLD-RNLSCRVVGVPYQ--GNATALFILPSE-GKMQQVENGLS 283

  Fly   254 DLDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASANLPIADVL 318
            :..|....:..:...:::.||||||:....|.:.|..||...:|.:.|:...:...:|:.:::::
Human   284 EKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMV 348

  Fly   319 QKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFAIRSENVTYL 375
            .|..:.::|||:.:........| ::...: ||.|..|.|   ||...|...|:.:|
Human   349 HKAVVEVDESGTRAAAATGTIFT-FRSARL-NSQRLVFNR---PFLMFIVDNNILFL 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	86/382 (23%)
SERPINA5	NP_000615.3	serpinA5_PCI	44..406	CDD:381021	82/371 (22%)