DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn31A and Serpinb3a

DIOPT Version :9

Sequence 1:	NP_609341.1	Gene:	Spn31A / 34339	FlyBaseID:	FBgn0032178	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	XP_006249702.1	Gene:	Serpinb3a / 498209	RGDID:	1562868	Length:	387	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	97/383 - (25%)
Similarity:	176/383 - (45%)	Gaps:	49/383 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMANFYAAELG 82
            :|..:..|  |.|:..|||.:...|::|.||:.|.|.::::|.:    :|....|.....:|:..
  Rat    15 LYRQLRDS--EDNIFYSPLSIMTALAMLQLGAKGNTEKQIEKVI----QFHETTKKTTEKSADCH 73

  Fly    83 NITTDADTFLQLQNRLMLSSES---------------GVADDFQKIAQTYFHATAECVDL----- 127
            :..:..:.|.:|..:|..|:::               .....|.:..:.|:.|..|.:|.
  Rat    74 DEESVHEQFQKLMTQLNKSNDAYDLNSANSIYGAKHFPFLQTFLEDIKEYYQANVESLDFAHAAE 138

  Fly   128 EQTEKLRRHISEQILASVGGGSWKDIHVAGGSSANTLLLLL-AANLQSKWFLPFSAYRTGLYEFH 191
            |..:|:...:..|.     .|..||:...|..:::|:|:|: |...:.:|...|....|...:|.
  Rat   139 ESEKKINSWVENQT-----NGKIKDLFPKGSLNSSTILVLVNAVYFKGQWNHKFDEKHTEEDKFW 198

  Fly   192 SGSQV-KSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQL--H 253
            ..... |.|.|:...:.| .|..|.|:.|:.:|:||: .:||||.::||.:..||::||:||  .
  Rat   199 LNKNTSKPVQMMRQKNEF-NFIFLEDVQAKMVEIPYK-GKELSMFILLPMEIDGLKKLEEQLTAD 261

  Fly   254 DLDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIF-AASANFKHLHASANLPIADV 317
            .|......:.|.|..:.:.||:|.::.:..|..||:.:|..:.| :..|:|..:.::..|.::.|
  Rat   262 KLLEWTRAENMNMIDLYLSLPRFKVEEKYDLPGPLQHMGMVDAFDSKKADFSGMSSTQGLMVSKV 326

  Fly   318 LQKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQ--KFFRADHPFFFAIRSENVT 373
            |.|..:.:||.|:        .|.....:.:|.:|.|  :.|..||||.|.|: .|.|
  Rat   327 LHKSFVEVNEEGT--------EAAAATGVEVSLTSAQITEDFNCDHPFLFLIK-HNAT 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	97/383 (25%)
Serpinb3a	XP_006249702.1	SERPIN	5..387	CDD:294093	97/383 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.930