Protein Alignment Spn31A and SERPINC1

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 86/427 - (20%)
• Similarity: 165/427 - (38%)
• Gaps: 88/427 - (20%)

  Fly    19 YHSIATSFAE-QNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMANFYAAELG 82
            |..:|.|..: .|:.:|||.:....::..||:...|.::|.:..:........:...:|:.|:|.
Human    95 YQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLN 159

  Fly    83 -NITTDADTFLQL--QNRLMLSSESGVADDFQKIAQTYFHATAECVDL-EQTEKLRRHISEQILA 143
             .:...|:...:|  .|||.........:.:|.|::..:.|..:.:|. |..|:.|..|::.:..
Human   160 CRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSN 224

  Fly   144 SVGGGSWKDIHVAGGSSANTLLLLLAAN------------------------------------- 171
            ...|   :...|....:.|.|.:|:..|
Human   225 KTEG---RITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKWRDRSPER 286

  Fly   172 -------LQSKWFLPFSAYRTGLYEFH-SGSQVKSVPMLFDDDMFVKFAELRDLDARAIELPYEH 228
                   .|..|...||...|....|: :..:..|..|::.:..| ::..:.: ..:.:|||::
Human   287 ANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKF-RYRRVAE-GTQVLELPFK- 348

  Fly   229 AEELSMLLILPNQRGGLQELEKQLHDLDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGF 293
            .::::|:||||.....|.::||:|....|......::...:.|.:|:|.|:...||::.|:.:|.
Human   349 GDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGL 413

  Fly   294 EEIFAASANFKHLHASANLP-----------IADVLQKLRINLNESGSGSGPELPKNATEYKPIV 347
            .::|:..        .:.||           ::|...|..:.:||.||        .|.....:|
Human   414 VDLFSPE--------KSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGS--------EAAASTAVV 462

  Fly   348 ISNSS---RQKFFRADHPFFFAIRSE--NVTYLMGHV 379
            |:..|   .:..|:|:.||...||..  |....||.|
Human   463 IAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRV 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	86/427 (20%)
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	86/427 (20%)