Protein Alignment Spn31A and SERPINA2

DIOPT Version :9

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 80/372 - (21%)
• Similarity: 159/372 - (42%)
• Gaps: 28/372 - (7%)

  Fly    18 IYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMANFYAAELG 82
            :|..:|......||:|:|..:....::|.||:...|..|:.:.|.:.......||:...:...|.
Human    64 LYKELADLSQTSNVLVTPTSVAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAKIHECFQQVLQ 128

  Fly    83 NITTDADTFLQLQ--NRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLRRHISEQILASV 145
            .::. .||.|||.  :.|.::....:.|.|.:..:..:|:.|..::...||:.:..|:..:....
Human   129 ALSR-PDTRLQLTTGSSLFVNKSMKLVDTFLEDTKKLYHSEASSINFRDTEEAKEQINNYVEKRT 192

  Fly   146 GGGSWKDIHVAGGSSANTLLLLL-AANLQSKWFLPFSAYRTGLYEFH-SGSQVKSVPMLFDDDMF 208
            |.   |.:.:......:|.|.|: ..:...||...|.|....:..|| ....:..|||:   :..
Human   193 GR---KVVDLVKHLKKDTSLALVDYISFHGKWKDKFKAEHIMVEGFHVDDKTIIRVPMI---NHL 251

  Fly   209 VKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQLHDLDLGALQQRMQMEGVQVLL 273
            .:|...||.:..:..|...:....:...|||:.: .:.:||::|....|..:|:...:..:.:..
Human   252 GRFDIHRDRELSSWVLAQHYVGNATAFFILPDPK-KMWQLEEKLTYSHLENIQRAFDIRSINLHF 315

  Fly   274 PKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASANLPIADVLQKLRINLNESGSGS--GPEL 336
            ||.||.....|::.|:.||..:||:..|:...:...|.|.::..:....:.::|.|:.:  .|.|
Human   316 PKLSISGTYKLKRVLRNLGITKIFSNEADLSGVSQEAPLKLSKAVHVAVLTIDEKGTEATGAPHL 380

  Fly   337 PKNA-TEYKPIVISNSSRQKFFRADHPFFFAIRSE--NVTYLMGHVV 380
            .:.| ::|:.::.           :.||...|:.:  |....:|.||
Human   381 EEKAWSKYQTVMF-----------NRPFLVIIKDDITNFPLFIGKVV 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	78/369 (21%)
SERPINA2	NP_006211.2	SERPIN	62..418	CDD:214513	80/372 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010