DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn31A and serpind1

DIOPT Version :9

Sequence 1:	NP_609341.1	Gene:	Spn31A / 34339	FlyBaseID:	FBgn0032178	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_878300.1	Gene:	serpind1 / 359841	ZFINID:	ZDB-GENE-030711-2	Length:	507	Species:	Danio rerio

Alignment Length:	402	Identity:	88/402 - (21%)
Similarity:	168/402 - (41%)	Gaps:	67/402 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DCHIGAGIYHSIATSFAE-QNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMA 74
            :...|..:|..:.....: .|::::|:.:...:.::.||....|.|:|.:.:    .||.....:
Zfish   138 NARFGFRLYRKLRNRLNQTDNILLAPVGISIAMGMMGLGVGPNTQEQLFQTV----GFAEFVNAS 198

  Fly    75 NFYAAELGNITTDADTFLQLQNRLM---------------LSSESGVADDFQKIAQTYFHATAEC 124
            |.|     :.:|....|.:|.:||.               :.....:.|.|:..|:||:.|..:.
Zfish   199 NHY-----DNSTVHKLFRKLTHRLFRRNFGYTLRSVNDLYVKRNVQIQDSFRADAKTYYFAEPQS 258

  Fly   125 VDL----------EQTEKLRRHISEQILASVGGGSWKDIHVAGGSSANTLLLLLAANLQSKWFLP 179
            ||.          ::.:|:.:.:.::.|.||      |.::|       ::||.....:..|...
Zfish   259 VDFADPAFLVKANQRIQKITKGLIKEPLKSV------DPNMA-------VMLLNYLYFKGTWEQK 310

  Fly   180 FSAYRTGLYEF--HSGSQVKSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSMLLILPNQR 242
            |....|...:|  :...||: |.|:.:...::..|: .:|:...::|||  |..:|||:.:|.:.
Zfish   311 FPKELTHHRQFRVNEKKQVR-VLMMQNKGSYLAAAD-HELNCDILQLPY--AGNISMLIAVPQKL 371

  Fly   243 GGLQELEKQLHDLDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLH 307
            .|::.||:::....:......|.....:|:.|:|.::....|.:.||::|..:||....:|..:
Zfish   372 SGMRSLEQEISPTLVNKWLSNMTNRTREVVFPRFKLEQNYDLIEHLKEMGMTDIFTEKGDFSPM- 435

  Fly   308 ASANLPIADVLQKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFAI---RS 369
            .|..:.|.....:..|.:||.|:        .|.....|.....|.|..|..|.||.|.|   |:
Zfish   436 TSEKVIINWFKHQGSITVNEEGT--------EAAAMTHIGFMPLSTQTRFIVDRPFLFLIYEHRT 492

  Fly   370 ENVTYLMGHVVE 381
            ..|.: ||.||:
Zfish   493 GCVVF-MGRVVD 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	85/391 (22%)
serpind1	NP_878300.1	HCII	61..505	CDD:239002	88/402 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020