DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn31A and LOC299282

DIOPT Version :9

Sequence 1:	NP_609341.1	Gene:	Spn31A / 34339	FlyBaseID:	FBgn0032178	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_001376144.2	Gene:	LOC299282 / 299282	RGDID:	3745	Length:	413	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	87/366 - (23%)
Similarity:	171/366 - (46%)	Gaps:	23/366 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMANFYAAELG 82
            :|..:|....::|||.|||.:.|.|::|.||:..:|.||:.:.|:......:..::...:...|.
  Rat    56 LYKKLALRNPDKNVVFSPLSISAALTILSLGAKDSTMEEILEGLKFNLTEITEEEIHQGFGHLLQ 120

  Fly    83 NITTDADTF-LQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLRRHISEQILASVG 146
            .::...|.. :...:.|.:..|..:..:||:..:..:.|.|...|.:|..:.::.|::.:.....
  Rat   121 RLSQPEDQVEINTGSALFIDKEQPILSEFQEKTRALYQAEAFIADFKQPNEAKKLINDYVSNQTQ 185

  Fly   147 GGSWKDIHVAGGSSANTLLLLLAANL-QSKWFLPFSAYRTGLYEFHSGSQ--VKSVPMLFDDDMF 208
            |   |...:.......|.::|:...| :.||.:||:...|...||:...:  || |||:...::.
  Rat   186 G---KIAELFSDLEERTSMVLVNYLLFKGKWKVPFNPNDTFESEFYLDEKRSVK-VPMMKIKEVT 246

  Fly   209 VKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQLHDLDLGALQQRMQMEGVQVL- 272
            ..:....:|....:||.|  ....|.|.|||:| |.:|::|..|....|...:..:....:..|
  Rat   247 TPYVRDEELSCSVLELKY--TGNASALFILPDQ-GKMQQVESSLQPETLKKWKDSLIPRIINDLR 308

  Fly   273 LPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASANLPIADVLQKLRINLNESGSGSGPELP 337
            :|||||..:.||::.|.:||.:::|:..|:...:..:.:|.::.|:.|..::::|:|:.:
  Rat   309 MPKFSISTDYSLKEVLPELGIKKVFSQQADLSRITGTKDLYVSQVVHKAVLDVDETGTEA----- 368

  Fly   338 KNATEYKPIVISNSSRQKFFRADHPFFFAIR---SENVTYL 375
             .|......||....|...|  :.||...|.   |:::.::
  Rat   369 -TAATGVATVIRRQPRTLNF--NRPFMVVITDMDSQSILFV 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	87/366 (24%)
LOC299282	NP_001376144.2	serpinA3_A1AC	36..413	CDD:381019	87/366 (24%)
LOC299282	NP_001376144.2	RCL	365..389		6/31 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010