Protein Alignment Spn31A and SERPINA11

DIOPT Version :9

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 89/367 - (24%)
• Similarity: 141/367 - (38%)
• Gaps: 86/367 - (23%)

  Fly     8 TPYDCHIGAGIYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAK 72
            ||...:....:|..:|.. |..|:..||:.:..||:||.||:...|:..:.:.|
Human    51 TPTITNFALRLYKELAAD-APGNIFFSPVSISTTLALLSLGAQANTSALILEGL----------- 103

  Fly    73 MANFYAAELGNITTDADT---FLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLR 134
              .|...|    |.:||.   |..|.:.|.|.|.....    |:..:.|        |::..|.|
Human   104 --GFNLTE----TPEADIHQGFRSLLHTLALPSPKLEL----KVGNSLF--------LDKRLKPR 150

  Fly   135 RHISEQILASVGGGSWKDIHVAGGSSAN---------------------------------TLLL 166
            :|..:.|         |:::.|...|||                                 |.::
Human   151 QHYLDSI---------KELYGAFAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMV 206

  Fly   167 LLAAN---LQSKWFLPFSAYRTGLYE--FHSGSQVKSVPMLFDDDMFVKFAELRDLDARAIELPY 226
            |  ||   .::||..|||.|:|...|  |........|||:...:|. :|  |.|.|.....|..
Human   207 L--ANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMH-RF--LYDQDLACTVLQI 266

  Fly   227 EHAEELSMLLILPNQRGGLQELEKQLHDLDLGALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQL 291
            |:......||:||:. |.::::|..|....|....|.:....:.:.||:|||....:|...|.|:
Human   267 EYRGNALALLVLPDP-GKMKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQI 330

  Fly   292 GFEEIFAASANFKHLHASANLPIADVLQKLRINLNESGSGSG 333
            |...|....|:|..:....|..|:.|..|..::::|.|:.:|
Human   331 GLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAG 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	87/357 (24%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	87/365 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010