DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn31A and Serpina3n

DIOPT Version :9

Sequence 1:	NP_609341.1	Gene:	Spn31A / 34339	FlyBaseID:	FBgn0032178	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_113719.3	Gene:	Serpina3n / 24795	RGDID:	3747	Length:	418	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	94/397 - (23%)
Similarity:	179/397 - (45%)	Gaps:	59/397 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 DCHIGAG-IYH---------------SIATSFA------------EQNVVVSPLLLEATLSLLFL 47
            ||.:|.. ::|               ||.|.||            ::|||.|||.:.|.|:::.|
  Rat    23 DCILGEDTLFHEDQDKGTQLDSLTLASINTDFAFSLYKKLALRNPDKNVVFSPLSISAALAVVSL 87

  Fly    48 GSDGATAEELQKQLRLKQRFASNAKMANFYAAELGNITTDADTF-LQLQNRLMLSSESGVADDFQ 111
            |:.|.:.||:.:.|:.........::...:...|..::...|.. :...|.|.:.....|..:||
  Rat    88 GAKGNSMEEILEGLKFNLTETPETEIHRGFGHLLQRLSQPRDEIQISTGNALFIEKRLQVLAEFQ 152

  Fly   112 KIAQTYFHATAECVDLEQTEKLRR----HISEQILASVGGGSWKDIHVAGGSSANTLLLLLAANL 172
            :.|:..:.|.|...|.:|:.:.::    ::|:|....:.|      .:...:...:::|:.....
  Rat   153 EKAKALYQAEAFTADFQQSREAKKLINDYVSKQTQGKIQG------LITNLAKKTSMVLVNYIYF 211

  Fly   173 QSKWFLPFSAYRTGLYEFHSGSQ--VKSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSML 235
            :.||.:||....|...||:||.:  || |||:..:|:...:....:|:...:||.|  ....|.|
  Rat   212 KGKWKVPFDPRDTFQSEFYSGKRRPVK-VPMMKLEDLTTPYVRDEELNCTVVELKY--TGNASAL 273

  Fly   236 LILPNQRGGLQELEKQLHDLDLGALQQRMQMEGV-QVLLPKFSIDFECSLRQPLKQLGFEEIFAA 299
            .|||:| |.:|::|..|....|...:..::...: ::.||||||..:.:|...|.:||.:|:|:.
  Rat   274 FILPDQ-GKMQQVEASLQPETLRRWKDSLRPSMIDELYLPKFSISADYNLEDVLPELGIKEVFST 337

  Fly   300 SANFKHLHASANLPIADVLQKLRINLNESG----SGSGPELPKNATEYKPIVISNSSRQKFFRAD 360
            .|:...:....:|.::.|:.|..:::.|:|    :.:|.:....:.:..|::|:         .|
  Rat   338 QADLSGITGDKDLMVSQVVHKAVLDVAETGTEAAAATGVKFVPMSAKLDPLIIA---------FD 393

  Fly   361 HPFFFAI 367
            .||...|
  Rat   394 RPFLMII 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	91/389 (23%)
Serpina3n	NP_113719.3	serpinA3_A1AC	37..418	CDD:381019	90/383 (23%)
Serpina3n	NP_113719.3	RCL	367..394		4/35 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010