Protein Alignment Spn31A and Serpina1a

DIOPT Version :10

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001239498.1
• Gene: Serpina1a / 20700
• MGIID: 891971
• Length: 436
• Species: Mus musculus
• Alignment Length: 390
• Identity: 88/390 - (22%)
• Similarity: 161/390 - (41%)
• Gaps: 50/390 - (12%)

  Fly    20 HSIATSFAE---------------QNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFAS 69
            |.|||:..:               .|:..||:.:....::|.|||.|.|..::.:.|:......|
Mouse    65 HEIATNLGDFAISLYRELVHQSNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQTS 129

  Fly    70 NAKMANFYAAELGNIT-TDADTFLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKL 133
            .|.:...:...|..:. .|::..|...|.|.::::..:.:.|.:.|:.::.|....|:..::|:.
Mouse   130 EADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEA 194

  Fly   134 RRHISEQILASVGGGSWKDIHVAGGSSANTLLLLLAAN---LQSKWFLPFSAYRTGLYEFH-SGS 194
            ::.|::.:.....|   |..........:|:..|  ||   .:.||..||....|...||| ..|
Mouse   195 KKVINDFVEKGTQG---KIAEAVKKLDQDTVFAL--ANYILFKGKWKKPFDPENTEEAEFHVDES 254

  Fly   195 QVKSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQLHD--LDL 257
            ....|||:....| :.......|.:..:.:.|  |...:.:.:||:. |.:|.||:.|..  :..
Mouse   255 TTVKVPMMTLSGM-LHVHHCSTLSSWVLLMDY--AGNATAVFLLPDD-GKMQHLEQTLSKELISK 315

  Fly   258 GALQQRMQMEGVQVLLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHL-HASANLPIADVLQKL 321
            ..|.:|.::  .|:..|:.||..|.:|:..:..||...||...|:...: ..:|.|.::..:.|.
Mouse   316 FLLNRRRRL--AQIHFPRLSISGEYNLKTLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKA 378

  Fly   322 RINLNESGSGSGPELPKNATEYKPIVISN---SSRQKFFRADHPFFFAIRSENV--TYLMGHVVE 381
            .:.::|:|           ||...:.:..   .|.....|.||||.|.|..|:.  ...:|.||:
Mouse   379 VLTIDETG-----------TEAAAVTVLQMVPMSMPPILRFDHPFLFIIFEEHTQSPIFLGKVVD 432

  Fly   382  381
            Mouse   433  432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	serpin42Dd-like_insects	10..382	CDD:381070	88/390 (23%)
Serpina1a	NP_001239498.1	serpinA1_A1AT	67..435	CDD:381012	87/388 (22%)