DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn31A and Serpine1

DIOPT Version :9

Sequence 1:	NP_609341.1	Gene:	Spn31A / 34339	FlyBaseID:	FBgn0032178	Length:	382	Species:	Drosophila melanogaster
Sequence 2:	NP_032897.2	Gene:	Serpine1 / 18787	MGIID:	97608	Length:	402	Species:	Mus musculus

Alignment Length:	403	Identity:	109/403 - (27%)
Similarity:	174/403 - (43%)	Gaps:	76/403 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GAGIYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMANFYAA 79
            |..::..:..:..::|||.||..:.:.|::|.:.:.|.|..::|..:..|......|......:.
Mouse    39 GVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNEKGTAHALRQLSK 103

  Fly    80 EL------GNITTDADTFLQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLRRHIS 138
            ||      ..|:|....|:|....|:    .|....|.|:.||    ..:.||..:.|:.|..|:
Mouse   104 ELMGPWNKNEISTADAIFVQRDLELV----QGFMPHFFKLFQT----MVKQVDFSEVERARFIIN 160

  Fly   139 EQILASVGGGSWKDIHVAGGSS----------ANTLLLLLAANLQSKWFLPFSAYRTGLYEFH-- 191
            :          |.:.|..|..|          ...|:|:.|.....:|..||....|....||
Mouse   161 D----------WVERHTKGMISDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQRLFHKS 215

  Fly   192 SGSQVKSVPMLFDDDMF--VKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQLHD 254
            .||.| ||||:...:.|  .:|.....|:...:||||: .:.|||.:..|        .||.:|
Mouse   216 DGSTV-SVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQ-GDTLSMFIAAP--------FEKDVH- 269

  Fly   255 LDLGALQQRMQMEGVQ------------VLLPKFSIDFECSLRQPLKQLGFEEIFAAS-ANFKHL 306
              |.||...:..|.::            ::|||||::.|..||.||::||..::|:|: |:|..|
Mouse   270 --LSALTNILDAELIRQWKGNMTRLPRLLILPKFSLETEVDLRGPLEKLGMPDMFSATLADFTSL 332

  Fly   307 HASANLPIADVLQKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFAIR--- 368
            .....|.:|..|||:||.:||||:     :..::|.:   |||..........|..|.|.:|
Mouse   333 SDQEQLSVAQALQKVRIEVNESGT-----VASSSTAF---VISARMAPTEMVIDRSFLFVVRHNP 389

  Fly   369 SENVTYLMGHVVE 381
            :|.:.: ||.|:|
Mouse   390 TETILF-MGQVME 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	106/396 (27%)
Serpine1	NP_032897.2	SERPIN	29..402	CDD:294093	109/403 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.110