Protein Alignment Spn31A and SERPINA3

DIOPT Version :9

• Sequence 1: NP_609341.1
• Gene: Spn31A / 34339
• FlyBaseID: FBgn0032178
• Length: 382
• Species: Drosophila melanogaster
• Sequence 2: NP_001076.2
• Gene: SERPINA3 / 12
• HGNCID: 16
• Length: 423
• Species: Homo sapiens
• Alignment Length: 368
• Identity: 85/368 - (23%)
• Similarity: 164/368 - (44%)
• Gaps: 23/368 - (6%)

  Fly    18 IYHSIATSFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRFASNAKMANFYAAELG 82
            :|..:.....::||:.|||.:...|:.|.||:...|..|:.|.|:......|.|::...:...|.
Human    60 LYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLR 124

  Fly    83 NITTDADTF-LQLQNRLMLSSESGVADDFQKIAQTYFHATAECVDLEQTEKLRRHISEQILASVG 146
            .:...:|.. |.:.|.:.:..:..:.|.|.:.|:..:.:.|...|.:.:...::.|::.:.....
Human   125 TLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTR 189

  Fly   147 G---GSWKDIHVAGGSSANTLLLLLAANLQSKWFLPFSAYRTGLYEFH-SGSQVKSVPMLFDDDM 207
            |   ...||:     .|...::|:.....::||.:||....|....|: |..:...|||:....:
Human   190 GKITDLIKDL-----DSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHL 249

  Fly   208 FVKFAELRDLDARAIELPYEHAEELSMLLILPNQRGGLQELEKQLHDLDLGALQQRMQMEGV-QV 271
            .:.:....:|....:||.|  ....|.|.|||:| ..::|:|..|....|...:..::...: ::
Human   250 TIPYFRDEELSCTVVELKY--TGNASALFILPDQ-DKMEEVEAMLLPETLKRWRDSLEFREIGEL 311

  Fly   272 LLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASANLPIADVLQKLRINLNESGSGSGPEL 336
            .||||||..:.:|...|.|||.||.|.:.|:...:..:.||.::.|:.|..:::.|.|:.:..
Human   312 YLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASA-- 374

  Fly   337 PKNATEYKPIVISN-SSRQKFFRADHPFFFAI---RSENVTYL 375
               ||..|..::|. ...:...|.:.||...|   .::|:.::
Human   375 ---ATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFM 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn31A	NP_609341.1	SERPIN	18..379	CDD:238101	85/368 (23%)
SERPINA3	NP_001076.2	serpinA3_A1AC	40..421	CDD:381019	85/368 (23%)
		RCL	369..394		5/29 (17%)
		O-glycosylated at one site	381..389		1/7 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010