| Sequence 1: | NP_477041.1 | Gene: | Pen / 34338 | FlyBaseID: | FBgn0267727 | Length: | 522 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002255.3 | Gene: | KPNA1 / 3836 | HGNCID: | 6394 | Length: | 538 | Species: | Homo sapiens |
| Alignment Length: | 532 | Identity: | 239/532 - (44%) |
|---|---|---|---|
| Similarity: | 326/532 - (61%) | Gaps: | 21/532 - (3%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 NSRQGSYKANSINTQDSRMRRHEVTIELRKSKKEDQMFKRRNI--NDEDLTSPLKELNGQSPVQL 69
Fly 70 S----------VDEIVAAMNSEDQERQFLGMQSARKMLSRERNPPIDLMIG-HGIVPICIRFLQN 123
Fly 124 TNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLAEQAVWALGNIAGDGAA 188
Fly 189 ARDIVIHHNVIDGILPLINNETPLSFLRNIVWLMSNLCRNKNPSPPFDQVKRLLPVLSQLLLSQD 253
Fly 254 IQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVPALRSVGNIVTGTDQQTD 318
Fly 319 VVIASGGLPRLGLLLQHNKSNIVKEAAWTVSNITAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQ 383
Fly 384 KEAAWAVTNTTTSGTPEQIVDLIEKYKILKPFIDLLDTKDPRTIKVVQTGLSNLFALAE---KLG 445
Fly 446 GT--ENLCLMVEEMGGLDKLETLQQHENEEVYKKAYAIIDTYFSNGDDEAEQELAPQEVNGALEF 508
Fly 509 NATQPKAPEGGY 520 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pen | NP_477041.1 | SRP1 | 2..517 | CDD:227396 | 237/527 (45%) |
| HEAT repeat | 70..102 | CDD:293787 | 10/41 (24%) | ||
| armadillo repeat | 108..140 | CDD:293788 | 14/32 (44%) | ||
| armadillo repeat | 148..184 | CDD:293788 | 21/35 (60%) | ||
| armadillo repeat | 190..225 | CDD:293788 | 12/34 (35%) | ||
| armadillo repeat | 359..396 | CDD:293788 | 19/36 (53%) | ||
| armadillo repeat | 402..437 | CDD:293788 | 12/34 (35%) | ||
| KPNA1 | NP_002255.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..36 | 11/27 (41%) | |
| Arm_3 | 33..516 | CDD:330530 | 222/485 (46%) | ||
| nuclear localization signal | 42..51 | 6/8 (75%) | |||
| ARM 1, truncated | 77..117 | 10/39 (26%) | |||
| HEAT repeat | 88..116 | CDD:293787 | 9/27 (33%) | ||
| ARM 2 | 118..161 | 22/42 (52%) | |||
| armadillo repeat | 128..154 | CDD:293788 | 12/25 (48%) | ||
| NLS binding site (major). /evidence=ECO:0000250 | 149..241 | 48/91 (53%) | |||
| armadillo repeat | 162..198 | CDD:293788 | 21/35 (60%) | ||
| armadillo repeat | 204..239 | CDD:293788 | 12/34 (35%) | ||
| ARM 4 | 207..245 | 15/37 (41%) | |||
| Binding to RAG1 | 245..437 | 99/192 (52%) | |||
| armadillo repeat | 256..281 | CDD:293788 | 17/24 (71%) | ||
| armadillo repeat | 289..325 | CDD:293788 | 18/35 (51%) | ||
| NLS binding site (minor). /evidence=ECO:0000250 | 318..406 | 47/87 (54%) | |||
| armadillo repeat | 373..409 | CDD:293788 | 18/35 (51%) | ||
| ARM 9 | 413..457 | 17/44 (39%) | |||
| armadillo repeat | 416..450 | CDD:293788 | 12/34 (35%) | ||
| ARM 10, atypical | 460..504 | 20/43 (47%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5064 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG54553 | |
| OrthoDB | 1 | 1.010 | - | - | D1111872at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000157 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100442 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 6 | 5.730 | |||||