DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Pen and Spag6

DIOPT Version :9

Sequence 1:NP_477041.1 Gene:Pen / 34338 FlyBaseID:FBgn0267727 Length:522 Species:Drosophila melanogaster
Sequence 2:NP_001001334.2 Gene:Spag6 / 381350 MGIID:3040687 Length:509 Species:Mus musculus


Alignment Length:379 Identity:79/379 - (20%)
Similarity:142/379 - (37%) Gaps:70/379 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   133 AAWALTNIASGTSDQTRCVIEHNAVPHFVALLQSKSMNLAEQAVWALGNIAGDGAAARDIVIHHN 197
            |||||..||...::.::.|::..|||..|..:|.....|...|..||.:|:.........|:...
Mouse   145 AAWALAYIARHNAELSQAVVDAGAVPLLVLCIQEPETALKRIAASALSDISKHSPELAQTVVDVG 209

  Fly   198 VIDGILPLINNETPLSFLRNIVWLMSNLCRNKNPSPPFDQVKRLLPVLSQLLLSQDIQVLADACW 262
            .|..:..:|.|... ...:.::..:|::.::............:.||:...|..:|..|..:||.
Mouse   210 AIAHLAQMILNPDE-KLKQQVLSALSHIAKHSVDLAEMVVEAEIFPVVLTCLKDKDDFVKKNACT 273

  Fly   263 ALSYVTDDDNTKIQAVVDSDAVPRLVKLLQMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLP 327
            .:..:........|.:|::..|..::..:...:.:|.:|.:..:|.:...::.....||.|.|:|
Mouse   274 LIREIAKHTPELSQLIVNAGGVAAVIDCIGSCKGNIRLPGIMMLGYMAAHSENLAMAVIISKGVP 338

  Fly   328 RLG-LLLQHNKSNIVKEAAWTVSNITAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQKEAAWAVT 391
            :|. .|.:..:.:|...|||.:..:.....:..:||                          |:|
Mouse   339 QLSDCLSEEPEDHIKAAAAWALGQVGRHTPEHARAV--------------------------AIT 377

  Fly   392 NT-----TTSGTPEQIVDLIEKYK--------------ILKPFIDLLDTKDPRTIKVVQTGLSNL 437
            ||     ....:||...||..|.|              .|:||  |.|. .|..:|.|....|.:
Mouse   378 NTLPVLLALYMSPESSEDLQVKSKKAIKNIIQKCTYLPALEPF--LYDA-PPNILKYVAGQFSKV 439

  Fly   438 F---ALAEKLGGTENLCLMVEEMGGLDKLETLQQHENEEVYKKAYAIIDTYFSN 488
            .   :.|.:|..|.         |||.|:        :|:..:..:|:..|.:|
Mouse   440 LPHDSKARRLFVTS---------GGLKKI--------QEIKAEPGSILQEYINN 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PenNP_477041.1 SRP1 2..517 CDD:227396 79/379 (21%)
HEAT repeat 70..102 CDD:293787
armadillo repeat 108..140 CDD:293788 5/6 (83%)
armadillo repeat 148..184 CDD:293788 11/35 (31%)
armadillo repeat 190..225 CDD:293788 5/34 (15%)
armadillo repeat 359..396 CDD:293788 6/41 (15%)
armadillo repeat 402..437 CDD:293788 13/48 (27%)
Spag6NP_001001334.2 armadillo repeat 34..70 CDD:293788
armadillo repeat 76..108 CDD:293788
armadillo repeat 127..152 CDD:293788 5/6 (83%)
SRP1 <161..>423 CDD:227396 56/290 (19%)
armadillo repeat 162..194 CDD:293788 10/31 (32%)
armadillo repeat 202..238 CDD:293788 5/36 (14%)
armadillo repeat 244..278 CDD:293788 7/33 (21%)
HEAT repeat 335..369 CDD:293787 8/33 (24%)
HEAT repeat 378..406 CDD:293787 8/27 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5064
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.