Protein Alignment Pen and ima-1

DIOPT Version :9

• Sequence 1: NP_477041.1
• Gene: Pen / 34338
• FlyBaseID: FBgn0267727
• Length: 522
• Species: Drosophila melanogaster
• Sequence 2: NP_001379139.1
• Gene: ima-1 / 179555
• WormBaseID: WBGene00002072
• Length: 524
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 117/541 - (21%)
• Similarity: 232/541 - (42%)
• Gaps: 118/541 - (21%)

  Fly     9 RQGSYKANSINTQDSRMRRHEVTIELRKSKKEDQMFKR-------RNINDEDLTSPLKEL-NG-Q 64
            |...||:|..:..:.|.:|.|..:::||::: |:.|:|       |:::.|:.:..||.: :| |
 Worm    12 RSKMYKSNVRDQNEMRRKRREDEVQIRKNRR-DEKFERNRQITVQRSLSHEETSELLKSVADGLQ 75

  Fly    65 SPVQLSVDEIVAAMNS---------------------EDQERQFLGMQSARKMLSRERNPPIDLM 108
            |..:.::.|.:..::.                     .|.....:..|:.|.::||      .|:
 Worm    76 SMQETTIHEALTVLHENLNNTVWTIHVLVKVQILHKLSDVYCNRVISQTTRLLISR------TLL 134

  Fly   109 IGHGIVPI----------CIRFLQNTNNSMLQFEAAWALTNIAS-GTSDQTRCVIEHNAVPHFVA 162
            ...||..:          ||:.|               :.||:: |:|:...|....:.....:.
 Worm   135 KISGIDEVKYERYSSDDRCIQSL---------------VFNISTYGSSEDILCDTFQSIACFIIR 184

  Fly   163 LLQSKSMNLAEQAVWALGNIAGDGAAARDIVIHHNVIDGILPLINNETPLSFLRNIVWLMSNLCR 227
            .:..:::                   |.|..|...:||.  ..||....|.  |:::||:...|.
 Worm   185 SITYRNL-------------------ALDCAIVSELIDA--STINMSIILH--RSLMWLVFLFCE 226

  Fly   228 NKNP-SPPFDQVKRLLPVLSQLLLSQDIQVLADA---CWALS-------YVTDDDNTKIQAVVDS 281
            ..:. ||..|::..||.::|..:.|.|..|..||   |.:|:       |::|   .|:
 Worm   227 KLDRCSPHVDEIAPLLEIISNGIQSTDAMVQTDAASSCASLAEWPPIYHYMSD---LKL------ 282

  Fly   282 DAVPRLVKLLQMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLPRL-GLLLQHNKSNIVKEAA 345
              ..:||..|:.|:.:........:.:|:..|...|:.:|.:|.|..| |.:   |.|.:.:|..
 Worm   283 --CSKLVANLRNDKGNARPKVKAGINSIIQATGYFTEEMIDAGLLEVLKGFV---NVSYMSQEVC 342

  Fly   346 WTVSNITAGNQKQIQAVIQAGIFQQLRTVLEKGDFKAQKEAAWAVTNTTTSGTPEQIVDLIEKYK 410
            :.:|||....::.|..:|.:|:.:::..|:|..::::::|||:.:.:...|...:.:..::| ..
 Worm   343 FIISNICVEGEQTIDKLISSGVLREVARVMEASEYRSRREAAFVICHCCASANQKHLEYVVE-LG 406

  Fly   411 ILKPFIDLLDTKDPRTIKVVQTGLSNLFALAEK--LGGTEN-LCLMVEEMGGLDKLETLQQHENE 472
            :|..|.|||...|...:..:...:..|....|.  |....| :.:.:||:|..:|||.|.:.::.
 Worm   407 MLSAFTDLLTCMDVSLVSYILDAIYLLLQFGEMRLLPDNSNPVAIKLEEIGCREKLEFLCESQSV 471

  Fly   473 EVYKKAYAIIDTYFSNGDDEA 493
            :::.:||.|||.::.  ||:|
 Worm   472 DIHARAYTIIDRFYV--DDDA 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pen	NP_477041.1	SRP1	2..517	CDD:227396	117/541 (22%)
		HEAT repeat	70..102	CDD:293787	6/52 (12%)
		armadillo repeat	108..140	CDD:293788	5/41 (12%)
		armadillo repeat	148..184	CDD:293788	1/35 (3%)
		armadillo repeat	190..225	CDD:293788	10/34 (29%)
		armadillo repeat	359..396	CDD:293788	8/36 (22%)
		armadillo repeat	402..437	CDD:293788	7/34 (21%)
ima-1	NP_001379139.1	SRP1	10..496	CDD:227396	117/541 (22%)
		armadillo repeat	319..348	CDD:293788	9/31 (29%)
		armadillo repeat	356..393	CDD:293788	8/36 (22%)
		armadillo repeat	399..430	CDD:293788	7/31 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5064
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23316
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910