Protein Alignment Trp1 and sec62

DIOPT Version :9

• Sequence 1: NP_723510.1
• Gene: Trp1 / 34333
• FlyBaseID: FBgn0011584
• Length: 428
• Species: Drosophila melanogaster
• Sequence 2: NP_001020701.1
• Gene: sec62 / 563660
• ZFINID: ZDB-GENE-050913-83
• Length: 394
• Species: Danio rerio
• Alignment Length: 412
• Identity: 153/412 - (37%)
• Similarity: 225/412 - (54%)
• Gaps: 70/412 - (16%)

  Fly    33 QKVDKPSKDEKNVAKWLKKNVKTKKTKFLSHIVEYFTSSKAIDALLKSKFT---EGSNPLFTTRE 94
            |:|.:|:|:||.|||:|:.|..||.|..:.|.|:||.:|||:|.||.||:.   :|...||||||
Zfish    12 QEVSEPTKEEKAVAKYLRFNCPTKSTNMMGHRVDYFVASKAVDCLLDSKWAKAKKGEEALFTTRE 76

  Fly    95 QVIEFLDVMLEHKFFHRAKKVPVTLEEIRGKSGGDKKADKEKTQDKEKDKAKDE---------KK 150
            .|:::.:.:|:.:|||||.||      ::.|...|.|.:|:|.::|||:|||.:         ||
Zfish    77 SVVDYCNRLLKKQFFHRALKV------MKKKPEKDVKKEKDKEKEKEKEKAKSDSSKEEEKKSKK 135

  Fly   151 DTDPEGDNGQGDGGASGNEKEK--------EKKEKKKRKIRLDMHPEQIFVDGSEAYVWIYDPIP 207
            |.|.:.|:...|     .:|||        :||:..|:|.:|:.|.:|:|:||:|.|.|||||:.
Zfish   136 DKDKKKDSEAAD-----TKKEKNDDSPGSPKKKKDVKKKFKLEPHDDQLFLDGNEVYFWIYDPVH 195

  Fly   208 LHYWIFGFILLLGAVGICLFPLWPPLLRKGVYYLSIAAAGFLVFILALTIVRLIVFIIVWALTGG 272
            ...:..|.||::..:...||||||..:|.||||||:||..|:..||.|.:.|.|:|:|:|.:|||
Zfish   196 FKTFAMGLILVIAVIAATLFPLWPAEMRVGVYYLSVAAGCFVASILLLAVARCILFLIIWLVTGG 260

  Fly   273 KLHFWIFPNLTEDVSFFASFWPLYESNYNSDPNNSSAKTDK-KSKSKDKKKEKESDAEDTAVDAD 336
            :.|||..||||.||.|..||.|||...|....:.|...:|| .|||.|..|.::||:||.:
Zfish   261 RHHFWFLPNLTADVGFIDSFRPLYTHEYKGPRSGSKKSSDKPDSKSADSSKAQKSDSEDKS---- 321

  Fly   337 GDADGDVDAEVSTLEPEKIELIKEHDTDMEIRKRRKVGADDYEEDDVDEEETKAQPKDSKAGTPR 401
                          :.||.|                   |:.:|||..:.|......|:.:....
Zfish   322 --------------DSEKKE-------------------DEEDEDDNKDMEEGGHQTDTDSDRRE 353

  Fly   402 NSGSDSESSSKDYEIISSSEVQ 423
            :.|| ..|:..|:|:|:..|::
Zfish   354 DEGS-QHSNGNDFEMITREELE 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trp1	NP_723510.1	Sec62	105..303	CDD:281790	90/214 (42%)
sec62	NP_001020701.1	Sec62	42..293	CDD:281790	111/261 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576437
Domainoid	1	1.000	178	1.000	Domainoid score	I3509
eggNOG	1	0.900	-	-		E1_COG5232
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3023
OMA	1	1.010	-	-		QHG49369
OrthoDB	1	1.010	-	-		D1474000at2759
OrthoFinder	1	1.000	-	-		FOG0005183
OrthoInspector	1	1.000	-	-		oto40160
orthoMCL	1	0.900	-	-		OOG6_107760
Panther	1	1.100	-	-	LDO	PTHR12443
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1311
SonicParanoid	1	1.000	-	-		X4215
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800