Protein Alignment bib and AQP7

DIOPT Version :9

• Sequence 1: NP_001260313.1
• Gene: bib / 34330
• FlyBaseID: FBgn0000180
• Length: 737
• Species: Drosophila melanogaster
• Sequence 2: NP_001161.1
• Gene: AQP7 / 364
• HGNCID: 640
• Length: 342
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 74/290 - (25%)
• Similarity: 108/290 - (37%)
• Gaps: 76/290 - (26%)

  Fly    37 GHGVNNRLSSTLQAPKRSMQAEIRTLEFWRSIISECLASFM--YVFIVCGAAAGVGVGASVSSVL 99
            ||..:.|.|..:   ..|:.|:|:.: ..|.::.|.||.||  ||.:|      .|:|:....||
Human     6 GHRRSTRGSKMV---SWSVIAKIQEI-LQRKMVREFLAEFMSTYVMMV------FGLGSVAHMVL 60

  Fly   100 -------LATALASGLAMATLTQCFLHISGAHINPAVTLALCVVRSISPIRAAMYITAQCGGGIA 157
                   |...|..|..:.........|||||:|.|||.|.|.:..:...:..:|:..|..|...
Human    61 NKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFL 125

  Fly   158 GAALLYGV---TVPGYQGNLQAAISHSAALAA------------WERFGVEFILTFLVVLCYFVS 207
            .||.:|.:   .:..:.|. |..::...|.|.            |..|..|..||.::.||.|..
Human   126 AAATIYSLFYTAILHFSGG-QLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAI 189

  Fly   208 TDPMKK--FMGNSAASIG-------------CAYSACCFVSMPYLNPARSLGP---SFVL----- 249
            ||....  ..|..|..||             ..|:         :||:|.|.|   :|:.
Human   190 TDQENNPALPGTEALVIGILVVIIGVSLGMNTGYA---------INPSRDLPPRIFTFIAGWGKQ 245

  Fly   250 ------NKWDSHWVYWFGPLVGGMASGLVY 273
                  |.|   ||....||:|....|::|
Human   246 VFSNGENWW---WVPVVAPLLGAYLGGIIY 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bib	NP_001260313.1	MIP	58..273	CDD:278651	67/267 (25%)
AQP7	NP_001161.1	MIP	31..280	CDD:412216	67/261 (26%)
		NPA 1. /evidence=ECO:0000250|UniProtKB:P55064	94..96		1/1 (100%)
		NPA 2. /evidence=ECO:0000250|UniProtKB:P55064	226..228		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0580
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2356
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840