DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bib and Aqp2

DIOPT Version :9

Sequence 1:	NP_001260313.1	Gene:	bib / 34330	FlyBaseID:	FBgn0000180	Length:	737	Species:	Drosophila melanogaster
Sequence 2:	NP_037041.3	Gene:	Aqp2 / 25386	RGDID:	2142	Length:	271	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	101/284 - (35%)
Similarity:	152/284 - (53%)	Gaps:	33/284 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 EIRTLEFWRSIISECLASFMYVFIVCGAAAGVGVGASVSSVLLATALASGLAMATLTQCFLHISG 122
            |:|::.|.|::::|.||:.::||...|:|.   ..||....:|..|:|.||.:.||.|...|:||
  Rat     3 ELRSIAFSRAVLAEFLATLLFVFFGLGSAL---QWASSPPSVLQIAVAFGLGIGTLVQALGHVSG 64

  Fly   123 AHINPAVTLALCVVRSISPIRAAMYITAQCGGGIAGAALLYGVTVPGYQGNLQAAISHSAALAAW 187
            ||||||||:|..|...:|.:|||.|:.||..|.:||||:|:.:|....:|:|.....|:.|.|.
  Rat    65 AHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPVEIRGDLAVNALHNNATAG- 128

  Fly   188 ERFGVEFILTFLVVLCYFVSTDPMK-KFMGNSAASIGCA----------YSACCFVSMPYLNPAR 241
            :...||..||..:|||.|.|||..: ..:|:.|.|||.:          ::.|.      :||||
  Rat   129 QAVTVELFLTMQLVLCIFASTDERRGDNLGSPALSIGFSVTLGHLLGIYFTGCS------MNPAR 187

  Fly   242 SLGPSFVLNKWDSHWVYWFGPLVGGMASGLVYEYIFNSRNRNLRHN----KGSIDNDSSSIHSED 302
            ||.|:.|..|:|.|||:|.|||||.:...|:|.|:.....::|:..    || ::.|:.....|.
  Rat   188 SLAPAVVTGKFDDHWVFWIGPLVGAIIGSLLYNYLLFPSAKSLQERLAVLKG-LEPDTDWEEREV 251

  Fly   303 ELNYDMDMEKPNKYQQSQGTYPRG 326
            .....:::..|.       :.|||
  Rat   252 RRRQSVELHSPQ-------SLPRG 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bib	NP_001260313.1	MIP	58..273	CDD:278651	90/225 (40%)
Aqp2	NP_037041.3	MIP	3..219	CDD:395174	90/225 (40%)
		NPA 1. /evidence=ECO:0000250\|UniProtKB:P41181	68..70		1/1 (100%)
		NPA 2. /evidence=ECO:0000250\|UniProtKB:P41181	184..186		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	251..271		4/25 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152704at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920