Protein Alignment Dref and Zbed6

DIOPT Version :10

• Sequence 1: NP_523529.1
• Gene: Dref / 34328
• FlyBaseID: FBgn0015664
• Length: 709
• Species: Drosophila melanogaster
• Sequence 2: NP_001385760.1
• Gene: Zbed6 / 103693666
• RGDID: 9238526
• Length: 983
• Species: Rattus norvegicus
• Alignment Length: 818
• Identity: 143/818 - (17%)
• Similarity: 268/818 - (32%)
• Gaps: 264/818 - (32%)

  Fly     6 PASPVAIGELKYEDVSQLNFSKLYSPKMK--------------------------------SVYW 38
            |:||.:.|..:|.....|:.:::...:.|                                |..|
  Rat   207 PSSPGSNGSFEYIPTDSLDENRMGKKRDKSASDALRAKRGRFLIKSNIVKHALIPGTRAKTSAVW 271

  Fly    39 RYFGFPSNDNNEVITKQNVVCIKCHKVLT-----NHGNTTNLRAHLQHRHKDLFKELCQEHDIHV 98
            .:|   ..|...:   ...||..|.:.::     :|..|:.|:.|||           ..|.||.
  Rat   272 NFF---YTDPQHI---SRAVCNICKRSVSRGRPGSHLGTSTLQRHLQ-----------ATHPIHW 319

  Fly    99 PPRKTPRNVSHPPLSKRNVSSRRVKLEFINNRNH-------------DNASDDELDEAAVATAAM 150
            .............|.:....|.    :.:|:..|             |.:..|:.||..|    :
  Rat   320 AVANKDSGAIGNGLDETETESG----DLLNDTLHGEKSSGSQDLTAEDLSDSDDTDEPPV----L 376

  Fly   151 QAEEDASSQTMLYETMVPFTYDEAENLVEEEERLVMEPKYGRKRKVATPSSALMHGRVIKHEEGG 215
            :.|..:.|         |....|.:||...:|           |:..|.:          |.|.
  Rat   377 EVENRSES---------PIPVAEQDNLAHTQE-----------RETTTDT----------HCED- 410

  Fly   216 YAAVANIANLAEALTDIVIKDLRNVDSLYDAGFGEFLRQVLGNSAAMPE---------PHKIDSL 271
                |..:.:::|:..::::||...:......|..|| |::.....:|.         |...||:
  Rat   411 ----AASSQISQAVIQMIVEDLHPYNYFSTPAFQRFL-QIVAPDYRLPSETYFFTKAVPQLYDSV 470

  Fly   272 INEMHASKFLEIGEITRDFTSEKPFSLAFEMWVNVEQRRFLSIFHHFLDEETHS----------- 325
            ..::.         :|.:....:...|..::|.:.....:..:..|::..||.|
  Rat   471 REKIF---------LTLENVQSQKIHLTVDIWTHDPSTDYFIVTVHWVSLETASSPSNGGTPNFR 526

  Fly   326 ------VRGM----LYATV--EYNDYIVF----DDLLTDFYLANCTLAIINYDEEEDLLHTYLRE 374
                  |.|:    |...:  |.||.|..    :.|:..|.:::.:..:::..:.....|
  Rat   527 KWAVLCVTGLAKDCLITNILQELNDQIGLWLSPNFLIPSFIVSDNSSNVVHAIKGGGFTH----- 586

  Fly   375 KNIPISLCYVSVIDKCLRRVF-EIEEVATLLEQVKDLMQRHSTEIASKVSEVPMPTYNEH-FPW- 436
              :|   |::..::..::..| |.:.:..:|...:......|..:  |..::.....|:| .||
  Rat   587 --VP---CFLHCLNIVIQDFFCEHKSIENMLVAARKTCHHFSHSV--KARQILQEFQNDHQLPWK 644

  Fly   437 ------------TLYETLKFFAESISWSEDMDHLVISAKTVTEALSALVIALDTLRGEDIPLCSM 489
                        |.| .||:..|.   ...:.|.:..|..|  .|::|...|.|.      :|.:
  Rat   645 NLKQDETGHWISTFY-MLKWLLEH---CYSVHHSLGRASGV--VLTSLQWTLMTY------VCDI 697

  Fly   490 LSPI---TSKILIKKLGIAE----------------QD-------------DPLMMNLKRTISSV 522
            |.|.   |.::.:|..|:.:                :|             |.|.:.|:   |..
  Rat   698 LKPFEEATQRVSVKTTGLNQVLPIIHHLLFSLQRLREDFQVRGITQALNLVDSLSLKLE---SDA 759

  Fly   523 LQAHVISNDNLTAAALLDPRFHRLTTIDNLERTVRMLTHK---------YNINFGGVGEGESNEV 578
            |.:.::.:.:...|.||||.| :.:..|...:...:.|:|         |..:..|..:..|:|.
  Rat   760 LLSAMLKSKHCILATLLDPCF-KNSLEDFFPQGADLETYKQILAEEVCNYMESSPGACQIASSEA 823

  Fly   579 A------ATSSVVAIK---SEPRVVDGSAPKKLGL---KLLFDSNEIPNPPKRDADSSVESDLKR 631
            :      .|.|..:||   |....:|.||...:.:   ..||.|          |.:.|:...|.
  Rat   824 SGPLVRLGTDSFTSIKEGTSSAGSMDSSAADSVAIGSRSFLFPS----------AVAVVDEYFKE 878

  Fly   632 YRNEVVVQLDESPIEWWLKMGHIYGTLRDLASLYHSVP 669
            ..:|  :...:.|:.:|.:...|:..|..:|..|.|.|
  Rat   879 KYSE--LSGGDDPLVYWQRKVSIWPALTQVAIQYLSCP 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dref	NP_523529.1	zf-BED	35..84	CDD:427043	13/53 (25%)
Zbed6	NP_001385760.1	ZnF_BED	135..182	CDD:214746
		ZnF_BED	270..316	CDD:214746	12/62 (19%)
		Dimer_Tnp_hAT	873..953	CDD:399013	10/44 (23%)