DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5846 and ankra2

DIOPT Version :9

Sequence 1:	NP_001303318.1	Gene:	CG5846 / 34326	FlyBaseID:	FBgn0032171	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_001006692.1	Gene:	ankra2 / 448315	XenbaseID:	XB-GENE-1002386	Length:	312	Species:	Xenopus tropicalis

Alignment Length:	237	Identity:	76/237 - (32%)
Similarity:	114/237 - (48%)	Gaps:	20/237 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ANTIQTNANSD---------DDEGVRSAPTSML----VLDAKRKSAFLPYRPQSTVLTNLQRGNT 56
            :..||...|||         .:..:.::|:..:    |........|.|.: |||.|||..|||
Frog    76 SKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTTKHFSPIK-QSTTLTNKHRGN- 138

  Fly    57 EATFCPVEV-SLSFHERAGQGEITEEQVAAERARQQN-IDYKDAHGFTALHWAASYGQLVSVQLL 119
            |.:..|:.| |||.|:.|.|||:.   ..|.|..|:| ::..|..|||.|.|||::||:..|:.|
Frog   139 EVSTTPLLVNSLSVHQLAAQGEMV---YLASRLEQENVVNLTDEEGFTPLMWAAAHGQIAVVEFL 200

  Fly   120 VAAGANVNTMAPDLISPLLLAAAGGHNEIVRFLLEHGADSGHMDIVGNTALMYAAAGNHPHTCNE 184
            :..||:...:.....|.|.||.:.|:.:||:.|:|.|.|....|..|.|.|:||..|||......
Frog   201 LQNGADPQVLGKGRESALSLACSKGYTDIVKMLVECGVDVNEYDWNGGTPLLYAVHGNHVKCVKI 265

  Fly   185 LLAKDLDLSATNEDGDTAYSLAVEHGAHLAQALLEQYMTAII 226
            ||....|.:...:.|..:..|:|..|....|.::|.::..::
Frog   266 LLENGADPTIETDSGYNSMDLSVALGHRSVQQVIETHLLQLL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5846	NP_001303318.1	ANK	94..218	CDD:238125	42/123 (34%)
		ANK repeat	99..130	CDD:293786	13/30 (43%)
		Ank_2	104..196	CDD:289560	33/91 (36%)
		ANK repeat	132..163	CDD:293786	11/30 (37%)
		ANK repeat	165..196	CDD:293786	11/30 (37%)
		Ank_2	170..234	CDD:289560	15/57 (26%)
ankra2	NP_001006692.1	Ank_2	<132..209	CDD:372319	34/80 (43%)
		ANK repeat	143..178	CDD:293786	14/37 (38%)
		ANK repeat	180..211	CDD:293786	13/30 (43%)
		Ank_2	185..275	CDD:372319	33/89 (37%)
		ANK repeat	213..244	CDD:293786	11/30 (37%)
		ANK repeat	246..276	CDD:293786	11/29 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4820
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1348558at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48581
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5508
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.090