DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5846 and rfxank

DIOPT Version :9

Sequence 1:	NP_001303318.1	Gene:	CG5846 / 34326	FlyBaseID:	FBgn0032171	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	XP_002936373.2	Gene:	rfxank / 100490142	XenbaseID:	XB-GENE-1004063	Length:	238	Species:	Xenopus tropicalis

Alignment Length:	216	Identity:	76/216 - (35%)
Similarity:	110/216 - (50%)	Gaps:	19/216 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 QTNANSDDDEGVRSAPTSMLVLDAKRKSAFLPYRPQSTVLTNLQRGNTEATFCPVEVSLSFHERA 73
            |..:.||.:|.|       |.|:|    ..|.|   ||.|||.||||..:.......|||..:.|
Frog    32 QAQSGSDVEEDV-------LPLNA----GPLQY---STTLTNRQRGNMVSVLPATLDSLSVQQLA 82

  Fly    74 GQGEITE--EQVAAERARQQNIDYKDAHGFTALHWAASYGQLVSVQLLVAAGANVNTMAPDLISP 136
            .|||:|:  |.:..::|.   |:..|..|||.|.|||::|::.:|:.|:..||:.:.:|.:..|.
Frog    83 AQGELTQLKEYIQKDKAL---INCPDERGFTPLMWAAAFGEIETVRYLLELGADPHILAKERESA 144

  Fly   137 LLLAAAGGHNEIVRFLLEHGADSGHMDIVGNTALMYAAAGNHPHTCNELLAKDLDLSATNEDGDT 201
            |.||:.||:::||..||....|....|..|.|.|:||..|||......||.:..||:...:.|.|
Frog   145 LSLASTGGYSDIVTLLLSKKVDINIYDWNGGTPLLYAVRGNHMKCVEVLLERGADLTMEADSGYT 209

  Fly   202 AYSLAVEHGAHLAQALLEQYM 222
            ...|||..|....|.::|.::
Frog   210 PMDLAVALGYKKVQQVIEHHI 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5846	NP_001303318.1	ANK	94..218	CDD:238125	45/123 (37%)
		ANK repeat	99..130	CDD:293786	12/30 (40%)
		Ank_2	104..196	CDD:289560	34/91 (37%)
		ANK repeat	132..163	CDD:293786	11/30 (37%)
		ANK repeat	165..196	CDD:293786	12/30 (40%)
		Ank_2	170..234	CDD:289560	18/53 (34%)
rfxank	XP_002936373.2	PHA02875	6..>169	CDD:165206	55/153 (36%)
		ANK repeat	107..138	CDD:293786	12/30 (40%)
		Ank_2	112..202	CDD:372319	34/89 (38%)
		ANK repeat	140..171	CDD:293786	11/30 (37%)
		ANK repeat	173..203	CDD:293786	12/29 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2760
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4820
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1348558at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48581
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5508
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.090