DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4658 and mtd

DIOPT Version :9

Sequence 1:	NP_001285789.1	Gene:	CG4658 / 34325	FlyBaseID:	FBgn0032170	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001246928.1	Gene:	mtd / 45467	FlyBaseID:	FBgn0013576	Length:	1344	Species:	Drosophila melanogaster

Alignment Length:	533	Identity:	95/533 - (17%)
Similarity:	179/533 - (33%)	Gaps:	150/533 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 KSSDASHNGVSDVGGSHNNLKVT----QAQGSMTRSASGADVTEKYLTQLVPVEKLAEILREQTS 90
            :|.||...|...|....:::..:    .||.:..:||:.| ||:|      ..:|..::|:..:.
  Fly   795 QSLDAGTGGAGGVRKKTSSVSFSVDDEAAQQAQAQSAALA-VTDK------QADKKNKMLKRLSY 852

  Fly    91 SKLGINGIVAD------------------------------------VFVSQVFPQYADLGQRLF 119
            ....:.|:..:                                    ||.|......::||..||
  Fly   853 PLTWVEGLTGEGGAVPPGGVGSGSLNKSGDTDSAPNTGDSNQSVFSKVFSSSPITLVSELGGNLF 917

  Fly   120 NLMHSNSKA----------TTKHLGAVAF-RQQCERFL------GIMDDSKTLEC-------YIK 160
            :...|....          :|...|.:.: |.....|:      |....:|..|.       |..
  Fly   918 SKTPSEDSGGSPVPPLTPHSTHSEGHMTYGRSSIGTFIRPHSSEGTSSSTKLKEAKQAPKLDYRS 982

  Fly   161 MYAQEENPD---QIDKTGVTRLLHICYTIAM-------QHSGNAVLCPAINRTFGSVTKSIFLCH 215
            |.:.::.|:   .:||. :.|....|....:       :..|.|:..|....::|.
  Fly   983 MVSMDDKPELFISVDKL-IPRPARACLDPPLYLRLRMGKPIGKAIPLPTSVMSYGK--------- 1037

  Fly   216 DSMSLGYVCRWF---EQNLMRLVLLVHKYCVHTLSTAYRGL-EQQNQSCGIELQTPVLEQRNPFT 276
            :.:...|   ||   :..:..|...::.:..|    .|..| |:|.::.|.||.....|.....|
  Fly  1038 NKLRAEY---WFSVPKNRVDELYRFINTWVKH----LYGELDEEQIKARGFELIQEDTEWTKSGT 1095

  Fly   277 DTTDFSGGSTREMDSLMPLS-QAW-LLAGALPPLYSKPQTVTPPATK-----GNNNVSAST---- 330
            ......||| ::.:.:..|: ::| |:.......|...:|.:..|:.     |...:|.||
  Fly  1096 TKAGMGGGS-QDGEEISDLTRESWELIKAPFAKTYKIIKTASHAASHDLEMLGGEVLSMSTDEYR 1159

  Fly   331 AVQIF-------------------------KDKL-SMMPSH-----WTLLYNSNEHGVGANRFLH 364
            ...:|                         ::|| |.:|:.     |:|::::::||...|....
  Fly  1160 KTSLFATGSFDLDFPIPDLIGKTEILTEEHREKLCSHLPARAEGYSWSLIFSTSQHGFALNSLYR 1224

  Fly   365 HVLGYRGPTLVLLHTKDEQTY-CVASPSEWKETHLFVGGEGSCVIQLLPKFVILEKKPNILYLNT 428
            .:.....|.|:::...:...: .:.|.|.....|.:..|| |.:.:..|.|.:.......:|.
  Fly  1225 KMARLESPVLIVIEDTEHNVFGALTSCSLHVSDHFYGTGE-SLLYKFNPSFKVFHWTGENMYF-- 1286

  Fly   429 SIRGYPKGLRAGA 441
             |:|..:.|..||
  Fly  1287 -IKGNMESLSIGA 1298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4658	NP_001285789.1	TLDc	327..475	CDD:214733	29/151 (19%)
mtd	NP_001246928.1	LysM	271..371	CDD:224306
		LysM	329..371	CDD:279777
		TLDc	1182..1344	CDD:214733	25/121 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23354
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010