DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4709 and stip-1

DIOPT Version :9

Sequence 1:	NP_001285788.1	Gene:	CG4709 / 34324	FlyBaseID:	FBgn0032169	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_496226.2	Gene:	stip-1 / 174600	WormBaseID:	WBGene00007412	Length:	830	Species:	Caenorhabditis elegans

Alignment Length:	312	Identity:	70/312 - (22%)
Similarity:	119/312 - (38%)	Gaps:	85/312 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   254 DEDDELSSEESNSSMNDNSSDEAESDMDDLEEARRARMVELSLFTFKPTERLGA----------- 307
            |:||.       :|:|.|...|.:...||    ..:..::....|.|..::.||
Worm    82 DKDDP-------ASLNLNLGGEKKPKEDD----EGSIQIDFDKRTKKAPKQNGAQVFAGMRSSAN 135

  Fly   308 --------WEEFTRGIGS-----KLMEKMGYIHGTGLGSDGRGIVTPVSAQILPQGRSLDACMEL 359
                    :..:.||.|:     |:|:.|||..|.|||:.|:|||.||.|| |.:||........
Worm   136 HGAADINQFGSWMRGDGNSNKIMKMMQAMGYKPGEGLGAQGQGIVEPVQAQ-LRKGRGAVGAYGK 199

  Fly   360 REAANGDKDYFSVERKLKR------AQRRQRKADEKAYV------RESQRVDV-FTFLNDSVLGP 411
            ...|.|.|...|.....||      :.|......||:.:      ::||.|.. :..:.|.:
Worm   200 ESTATGPKFGESAADAQKRMAQEGTSSRPTNDDQEKSGLKIKGSWKKSQTVKTKYRTIEDVM--- 261

  Fly   412 GESTQQGEQVTKKAKTNELQQHSTKTLNVETVRIADEIRRKQR-----DMAKVKQSLDRNSGDAQ 471
                ::|...::.|...:.||:|       .:::.|...::|:     |...:|...:.::.|.:
Worm   262 ----EEGMSASRPASHQQSQQYS-------NIKVIDMTGKQQKIYSGYDSFSMKTRSEYDTVDDE 315

  Fly   472 LQKRLQVQMQSH----------------KQELATLQAQERSLSKE-QQTRKS 506
            .:....|....|                .|:|.:|:.|..:|..: ||.:||
Worm   316 ERTVFDVPELIHNLNLLVDLTEEGIRRSNQQLISLKDQTTALEYDLQQVQKS 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4709	NP_001285788.1	ZnF_C3H1	155..176	CDD:214632
CG4709	NP_001285788.1	G-patch	312..355	CDD:279867	23/47 (49%)
stip-1	NP_496226.2	TIP_N	4..104	CDD:289242	9/32 (28%)
		G-patch	154..197	CDD:279867	20/43 (47%)
		DUF1319	310..>411	CDD:284451	12/58 (21%)
		GCFC	397..673	CDD:285127
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1238995at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010