Protein Alignment CG13126 and METTL17

DIOPT Version :10

• Sequence 1: NP_609330.1
• Gene: CG13126 / 34323
• FlyBaseID: FBgn0032168
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: XP_054232593.1
• Gene: METTL17 / 64745
• HGNCID: 19280
• Length: 537
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 67/340 - (19%)
• Similarity: 114/340 - (33%)
• Gaps: 136/340 - (40%)

  Fly     3 APKQKWTQEEESALKSGVIKHGPGKWRTILKDPEFSGVLYLRSNVDLKDKWRNMSVMANGWGSRE 67
            :|::  |::.||  |.|:             :||.|..          |:|| :|..|:..|:.:
Human    89 SPQE--TRQHES--KPGL-------------EPEPSSA----------DEWR-LSSSADANGNAQ 125

  Fly    68 KSRLAVKRTFS----LPK-QEENSLALTNSLQSDEENVDATSGLQVSS-----------NPP--- 113
            .|.||.|...|    ||. :.::|..|.|.:.|.....|:.:...||.           ||.
Human   126 PSSLAAKGYRSVHPNLPSDKSQDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPSTTIVNPTIVL 190

  Fly   114 ---PRRPNVRLDSLI----------MEAIATLKEPGGCNKTTIGAYIEDQYHAPPDFKRLLS--- 162
               .|....||.||.          .::..|.::|     |:.|..||.:  |..|.:|::.
Human   191 LQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKP-----TSPGKAIEKR--AKDDSRRVVKSTQ 248

  Fly   163 -------------------TKLKYLTSCGKLVKVKR----------KYRIP-------------- 184
                               :|..|.|...::.|:.|          .|:.|
Human   249 DLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDTPEENPYFPTYKFPELPEIQQTSEDDDS 313

  Fly   185 ------------NSTPLSSHRRKG-LGVFGGK---QRTSSLPSPKTDIDEVNFQTRS-------Q 226
                        ..:|||..|.|. :....|:   :|:::||.|.......:...|:       :
Human   314 DLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKK 378

  Fly   227 IDTEIARMKSMNVHE 241
            :||...|.:..:::|
Human   379 VDTRKYRAEPKSIYE 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13126	NP_609330.1	Rsm22	156..441	CDD:401254	24/155 (15%)
METTL17	XP_054232593.1	AdoMet_MTases	214..480	CDD:473071	31/187 (17%)