DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13126 and cox1102

DIOPT Version :9

Sequence 1:	NP_001285787.1	Gene:	CG13126 / 34323	FlyBaseID:	FBgn0032168	Length:	463	Species:	Drosophila melanogaster
Sequence 2:	NP_001343002.1	Gene:	cox1102 / 5802969	PomBaseID:	SPAC19B12.13	Length:	753	Species:	Schizosaccharomyces pombe

Alignment Length:	485	Identity:	128/485 - (26%)
Similarity:	192/485 - (39%)	Gaps:	136/485 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SALEHATLKPRKHPGVVRPNHVELPKQLNDTLKRIVGDHPVKKLIHDGQQLNAYIKSRHPPPTLE 97
            |:|....:|.:|..|.: ..|.:....::|.||:..... :||.|:|
pombe    67 SSLLDFLVKDQKKSGDI-SLHTKFNLYVDDLLKKSEKGQ-IKKFIND------------------ 111

  Fly    98 EIENKKRIVIEEVNTKMPLDRLATLDEDEAERWRRKRELEINKRLGQRIYAWKRIEYGAYESLVY 162
               .||.:..|   :::|   |:...:||:.|.....::               :.| .::|:.|
pombe   112 ---IKKDLATE---SQLP---LSAPFKDESTRTMTDPQV---------------LAY-IHQSMPY 151

  Fly   163 AIARGAQEYAVLKRVLTEL--AQRDEQFRPRSFFDFGSGIGTGMWVASELWREHIFEYYNVDRSR 225
                   :||.|..|||:|  ...|...:.:...|.|.|.|.|     .|....:|...|.....
pombe   152 -------QYASLYSVLTDLKIVNSDVSCKSQHILDCGKGPGIG-----ALASYSVFPTPNSVSIV 204

  Fly   226 EMNEISELILRDGHEN----------KQIALRNVFYRQFLP-AIETNYDLVIISHTLFELENKEQ 279
            |.|...:.|:.|.|.|          ..:.|..      || ..:.:|.|||.|:.|.|::::::
pombe   205 EENPFLKKIIYDIHHNIYPSTSPNPTSPVTLNR------LPLGKKDSYTLVIASNKLLEMKSEKE 263

  Fly   280 REDVLRNLWRKCD---GYLVIVEEGTRRGSELVNEARQFLLEQEQ-------EGHTVAPCPHDLV 334
            ..|.||:||....   |.||:.|.||:||..|:..||.|||::.:       ..|.|||||||..
pombe   264 LFDYLRSLWSLVSNDGGLLVLCERGTKRGFSLIQRARTFLLQKSKNTSDKQFNAHIVAPCPHDGR 328

  Fly   335 CP-RLRDLADRTPCNF-------PIS--YAPL--RLGSDFLADRHTSLYSYAILKKG-------- 379
            || .:.:......|:|       |.|  |.|.  |..||      .|.|||.:::||
pombe   329 CPIDIENGVRANICSFKQHFFLSPFSRLYVPRSHRRSSD------RSHYSYVVIQKGITRPLNNT 387

  Fly   380 ---------------SQSDSSSSWPRIVRPTLVRSKHAICRLCTEKGTLQEVIFTKSKHGKSAYS 429
                           ..|.:..:||||:||.|.|..|.|..:|.....|:..|..||: ||.||.
pombe   388 TQRFKNDEDLLENVNVTSPTLKNWPRIIRPPLKRDGHVIIDVCDSDARLRRNIVPKSQ-GKLAYR 451

  Fly   430 CAKVSRWGDRLPMSLGQPQIKQESIESEEP 459
            .|:.|.|||..|:        :..::|..|
pombe   452 LARKSAWGDLFPL--------EGKVQSTSP 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13126	NP_001285787.1	Rsm22	156..441	CDD:286344	103/342 (30%)
cox1102	NP_001343002.1	Rsm22	59..561	CDD:227746	128/485 (26%)
cox1102	NP_001343002.1	COX11	565..753	CDD:225716
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	108	1.000	Domainoid score	I1640
eggNOG	1	0.900	-	-		E1_COG5459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810