Protein Alignment CG13126 and metl-17

DIOPT Version :10

• Sequence 1: NP_609330.1
• Gene: CG13126 / 34323
• FlyBaseID: FBgn0032168
• Length: 463
• Species: Drosophila melanogaster
• Sequence 2: NP_001382712.1
• Gene: metl-17 / 173356
• WormBaseID: WBGene00009305
• Length: 533
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 132/525 - (25%)
• Similarity: 224/525 - (42%)
• Gaps: 96/525 - (18%)

  Fly     2 NFSLNFTTRN-LVPRLHRFTSKIAVDVEPAVVSALEHATLKPRKHPGVVRPNHVELPKQLNDTLK 65
            :|..||.|.: ..||......|.|:....|:.:|.....:..::..|........||::..|.|:
 Worm    10 HFIANFATSSAFEPREFENNEKTAITAVNALTNARSIVQITSKEKVGKRFRREFNLPQKAIDGLR 74

  Fly    66 R--IVGDHPVKKLIHDGQQLNAYIKSRHPPPTLEEIENKKRIVIEEVNTKM---PLDRLATLDED 125
            .  |..:.|.|:|.::..||...::.|..|.:.|:::..:    :||..|:   ..|.::..|::
 Worm    75 NAIITCERPAKQLQNEADQLAKKLEQRRFPESPEKLKKLR----DEVKRKLKSGKKDEISDFDKE 135

  Fly   126 -------EAERWRRKRELEINKRLGQRIYAWKRIEYGAYES-LVYAIARGAQEYAVLKRVLTELA 182
                   ||:::..:.  |:::.:.:..:.||.:|....|| ..|::||.|..||.:.|.|.|.
 Worm   136 SFGGKVQEAQQYEIRN--EVDRIMKKENFNWKPLEITTKESAAAYSLARLAPNYAEITRTLEEF- 197

  Fly   183 QRDEQFRPRSFFDFGSGIGTGMWVASELWREHIFEYYNVDRSREMNEISELILRD------GHEN 241
            .....|:|.:..|||||.|.|.|.....|.: :.|...||.|..|.:.|...||:      ....
 Worm   198 NTIPDFQPETVLDFGSGAGAGFWAIQNKWPD-VKEITMVDLSDAMMKFSMDSLRNEQSSEASQNG 261

  Fly   242 KQIALRNV-FYRQFLPAIETNYDLVIISHTLFELENKEQREDVLRNLWRKCDGYLVIVEEGTRRG 305
            :.....|| |.|..:|::.|.||:|:....|.|:.:.|.|..::.:||::.:.:|:::|......
 Worm   262 RPFVHNNVNFRRHLIPSLNTTYDVVLAHRVLCEIGSSETRLQLIESLWKRTNRFLILIESSQTGA 326

  Fly   306 SELVNEARQFLLEQ-------------EQ-------------------------------EGHTV 326
            ...:.|||.|||.|             |:                               .||||
 Worm   327 FGGLLEARDFLLTQGTLVDYRKLLKSLEEAVMLSPKVVRIVEDYNLSDYEKYALLMEAVPPGHTV 391

  Fly   327 ----------APCPHDLVCPRLRDLADRTPCNFPISYAPLRLG---SDFLAD-RHTSLYSYAILK 377
                      |||||||.||    |...:.|.|...:.|:|..   |:..:| ...|.::|.||:
 Worm   392 PTMLPTATVLAPCPHDLGCP----LGVHSSCTFNTRFQPIRADGRRSEKESDGTEVSKFTYMILE 452

  Fly   378 KGSQSDSSSSWPRIVRPTLVRSKHAICRLCTEKGTLQEVIFTKSKHGK---SAYSCAKVSRWGDR 439
            |..:..::....||::...: ..|..|.:||....:|.:..:| |||:   :.:...:..|.||.
 Worm   453 KSQRKVNNEHTERILKNRKL-GGHVTCDVCTAFRGIQRITLSK-KHGEMYTAFFFQLRSRRDGDL 515

  Fly   440 LPMSL 444
            ||::|
 Worm   516 LPINL 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13126	NP_609330.1	Rsm22	156..441	CDD:401254	94/353 (27%)
metl-17	NP_001382712.1	AdoMet_MTases	172..517	CDD:473071	94/352 (27%)