Protein Alignment CG5853 and YOL075C

DIOPT Version :10

• Sequence 1: NP_788019.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_014567.2
• Gene: YOL075C / 854080
• SGDID: S000005435
• Length: 1294
• Species: Saccharomyces cerevisiae
• Alignment Length: 720
• Identity: 177/720 - (24%)
• Similarity: 321/720 - (44%)
• Gaps: 147/720 - (20%)

  Fly    64 QVNYTNGNE-PSKQPPLEPVVEEEVHFDTDALNNLPAREPVDME-FKELSLTVKL---------- 116
            :::.|..|| .|||..::......:..:...|:::..::.::.| .|.:.:|:||
Yeast   627 KIDITLQNEVKSKQKKIKKKSPTGMKPEIQLLDDVYHQKDLEAEKGKNIHITIKLEDIDLRVIFS 691

  Fly   117 ---------GFNRGSKEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSG------FKTTGVDG 166
                     .|:..:||||.:|...|....:.|||||||:|||:||:.:||      |......|
Yeast   692 APFSNWKEGNFHHETKEILQSVNAIFKPGMINAIMGPSGSGKSSLLNLISGRLKSSVFAKFDTSG 756

  Fly   167 SILLNGRRRDLPSFRRMSCYITQ-DDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLL 230
            ||:.|..:.....|:.:..|::| ||.|...|||.|.:..||.|:|......|..| |.::::..
Yeast   757 SIMFNDIQVSELMFKNVCSYVSQDDDHLLAALTVKETLKYAAALRLHHLTEAERME-RTDNLIRS 820

  Fly   231 LGLYNHDQTL-----TMRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKL- 289
            |||.:.:..:     ...:|||:|:|:::.::|:|:|.::.|||||:||||.:...:||:|:||
Yeast   821 LGLKHCENNIIGNEFVKGISGGEKRRVTMGVQLLNDPPILLLDEPTSGLDSFTSATILEILEKLC 885

  Fly   290 TSQGRTIICTIHQPTAKLFQIFDQVYVLS-AGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYII 353
            ..||:|||.|||||.::||:.|..|.:|: :|...:.||..:::.:...:...||.:.|.||:.:
Yeast   886 REQGKTIIITIHQPRSELFKRFGNVLLLAKSGRTAFNGSPDEMIAYFTELGYNCPSFTNVADFFL 950

  Fly   354 ELACGEYGYDKVDTLKLATENGSCLTWFHNPSAVLRAEVLMRKY----------PIPKKTKSRSL 408
            :|            :.:.|:|..     :..|:..|.|.::..:          |.|...|.:..
Yeast   951 DL------------ISVNTQNEQ-----NEISSRARVEKILSAWKANMDNESLSPTPISEKQQYS 998

  Fly   409 ED---TSYSN----------QCSVLLRRGFIKAKR--DTTMTHLR----IGVNIAVAALFGAMYD 454
            ::   |.||.          ...|.::|.|...:|  |:.|..:.    :||   :.|||.|...
Yeast   999 QESFFTEYSEFVRKPANLVLAYIVNVKRQFTTTRRSFDSLMARIAQIPGLGV---IFALFFAPVK 1060

  Fly   455 HTGREGSRVLDNYNLLFAILMHHSMTT------MMLTVLTFPMDISILIKEHFNRWYSLKAYYTA 513
            |          ||..:...|.....:|      |:..:..:|.:.....:|:.:..|.:..::.|
Yeast  1061 H----------NYTSISNRLGLAQESTALYFVGMLGNLACYPTERDYFYEEYNDNVYGIAPFFLA 1115

  Fly   514 MTLVDLPISIISCFFFTVIVYLWSYQPMEWIRFFMFFSISLLTVFVGHSFGLMIGAWFD----VV 574
            ...::||:|.::...:.|...|....|.....||.....|.:....|.:.|:|...:|:    ||
Yeast  1116 YMTLELPLSALASVLYAVFTVLACGLPRTAGNFFATVYCSFIVTCCGEALGIMTNTFFERPGFVV 1180

  Fly   575 N--------GTFLAPVLTIPM-MMFAGFGVTLRDLPSYLRWGSHIS--YLRYGLEGFISAIYGLD 628
            |        ||.::.::::.| .:..||        :||....:.|  .:.:...|.:.
Yeast  1181 NCISIILSIGTQMSGLMSLGMSRVLKGF--------NYLNPVGYTSMIIINFAFPGNLK------ 1231

  Fly   629 RGTLACEEA-----PYCHYRYPKKFLEEI-TMRGDQFWNDVIALGVMI---LVFRFVSYVVLKAK 684
               |.||:.     ..|.:......|... .:|..|.:     ||:::   :::|.:::.:||||
Yeast  1232 ---LTCEDGGKNSDGTCEFANGHDVLVSYGLVRNTQKY-----LGIIVCVAIIYRLIAFFILKAK 1288

  Fly   685 IKSIR 689
            ::.|:
Yeast  1289 LEWIK 1293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_788019.1	3a01204	97..689	CDD:273361	169/684 (25%)
YOL075C	NP_014567.2	3a01205	55..1236	CDD:273362	164/656 (25%)