Protein Alignment CG5853 and PDR15

DIOPT Version :9

• Sequence 1: NP_001260309.1
• Gene: CG5853 / 34322
• FlyBaseID: FBgn0032167
• Length: 689
• Species: Drosophila melanogaster
• Sequence 2: NP_010694.1
• Gene: PDR15 / 852015
• SGDID: S000002814
• Length: 1529
• Species: Saccharomyces cerevisiae
• Alignment Length: 614
• Identity: 158/614 - (25%)
• Similarity: 280/614 - (45%)
• Gaps: 88/614 - (14%)

  Fly    62 PPQVNYTNGNEPSKQPPLEPVVEEEVHFDTDALNN----LPAREPVDMEFKELSLTVKLGFNRGS 122
            |..:....|:.|......:.::::.......:.:|    |...|.: ..:::|...|.:  ..|.
Yeast   838 PGDIENNAGSSPDSATTEKKILDDSSEGSDSSSDNAGLGLSKSEAI-FHWRDLCYDVPI--KGGQ 899

  Fly   123 KEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTGV-DGSILLNGRRRDLPSFRRMSCY 186
            :.||:||.|......|.|:||.|||||:||||.|:...|.|| .|:|.::||.|| .||.|...|
Yeast   900 RRILNNVDGWVKPGTLTALMGASGAGKTTLLDCLAERVTMGVITGNIFVDGRLRD-ESFPRSIGY 963

  Fly   187 ITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTLTMRLSGG---- 247
            ..|.|......||.|::..:|.|:...:||.|||...:|:::.:|.:..:...:......|
Yeast   964 CQQQDLHLKTATVRESLRFSAYLRQPSSVSIEEKNRYVEEVIKILEMQQYSDAVVGVAGEGLNVE 1028

  Fly   248 QKKRLSIAMELINNPTVM-FLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIF 311
            |:|||:|.:||...|.:: ||||||:||||.:.....:|::||.:.|:.|:||||||:|.|.|.|
Yeast  1029 QRKRLTIGVELAARPKLLVFLDEPTSGLDSQTAWDTCQLMRKLATHGQAILCTIHQPSAILMQQF 1093

  Fly   312 DQ-VYVLSAGNCVYQG----STQKLVPFLQSVDL-PCPMYHNPADYIIEL---ACGEYG---YDK 364
            |: :::...|..||.|    ..:.::.:.:|... .||...|||::::|:   |.|.:.   |::
Yeast  1094 DRLLFLQKGGQTVYFGDLGEGCKTMIDYFESKGAHKCPPDANPAEWMLEVVGAAPGSHATQDYNE 1158

  Fly   365 V----DTLKLATENGSCLTWFHNPSAVLRAEVLMRKYPIPKKTKSRSLED-----TSYSNQCSVL 420
            |    |..|...|.   |.|             |.| .:|.::|..:.|:     .|...|..::
Yeast  1159 VWRNSDEYKAVQEE---LDW-------------MEK-NLPGRSKEPTAEEHKPFAASLYYQFKMV 1206

  Fly   421 LRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMY-DHTGREGSRVLDNYNLLFAILMHHSMTTMML 484
            ..|.|.:..|.......:.     :..:|..:: ..|..:..|.|..       |.:..::..|.
Yeast  1207 TIRLFQQYWRSPDYLWSKF-----ILTIFNQVFIGFTFFKADRSLQG-------LQNQMLSIFMY 1259

  Fly   485 TVLTFPMDISIL-----------IKEHFNRWYSLKAYYTAMTLVDLPISIIS-----CFFFTVIV 533
            ||:..|:....|           .:|..:|.:|..|::.:..:|::|.:|::     |.::..:.
Yeast  1260 TVIFNPILQQYLPSFVQQRDLYEARERPSRTFSWLAFFLSQIIVEIPWNILAGTIAYCIYYYAVG 1324

  Fly   534 YLWSY----QPMEWIRFFMFFSISLLTVFVGHSFGLMIGAWFDVV-NGTFLAPVLTIPMMMFAGF 593
            :..:.    |..|....|..|||:.. |::| |.||::.::.:|. ....:..:|....:.|.|.
Yeast  1325 FYANASAAGQLHERGALFWLFSIAFY-VYIG-SMGLLMISFNEVAETAAHMGTLLFTMALSFCGV 1387

  Fly   594 GVTLRDLPSYLRWGSHISYLRYGLEGFIS 622
            ..|.:.:|.:..:...:|.|.|.::..::
Yeast  1388 MATPKVMPRFWIFMYRVSPLTYMIDALLA 1416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	154/575 (27%)
		ABCG_EPDR	102..326	CDD:213180	87/230 (38%)
		ABC2_membrane	420..623	CDD:279410	41/225 (18%)
PDR15	NP_010694.1	ABC_trans_N	47..162	CDD:405234
		3a01205	110..1518	CDD:273362	158/614 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I1517
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13430
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R138
SonicParanoid	1	1.000	-	-		X52
TreeFam	0	0.000	Not matched by this tool.
	4	4.030