DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and ABCG25

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_565030.1	Gene:	ABCG25 / 843527	AraportID:	AT1G71960	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	695	Identity:	191/695 - (27%)
Similarity:	324/695 - (46%)	Gaps:	116/695 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 NYTNGNEPS---KQPPLEPVVEEEVHFDTDALNNLPARE--PVDMEFKELSLTVKL-GFNRGS-- 122
            |..||.:.|   .|.|.||             .:|.:..  |:.::|.::...||: |.:..|
plant     9 NQMNGPDSSPRLSQDPREP-------------RSLLSSSCFPITLKFVDVCYRVKIHGMSNDSCN 60

  Fly   123 --------------------KEILHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSG-FKTTGVDG 166
                                :.||..|.|.....:.:|::||||:||||||:|::| ...:.:.|
plant    61 IKKLLGLKQKPSDETRSTEERTILSGVTGMISPGEFMAVLGPSGSGKSTLLNAVAGRLHGSNLTG 125

  Fly   167 SILLNGRRRDLPSFRRMSCYITQDDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLL 231
            .||:|..:....:.:|.. ::.|||.|.|.|||.|.:...|.|:|.::::.:.|....|.::..|
plant   126 KILINDGKITKQTLKRTG-FVAQDDLLYPHLTVRETLVFVALLRLPRSLTRDVKLRAAESVISEL 189

  Fly   232 GLYNHDQTLT-----MRLSGGQKKRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLT- 290
            ||...:.|:.     ..:|||::||:|||.||:.||:::.|||||:|||:::..::::.|..|.
plant   190 GLTKCENTVVGNTFIRGISGGERKRVSIAHELLINPSLLVLDEPTSGLDATAALRLVQTLAGLAH 254

  Fly   291 SQGRTIICTIHQPTAKLFQIFDQVYVLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIEL 355
            .:|:|::.:||||::::||:||.|.:||.|.|::.|..:..:.:.:||........||||::::|
plant   255 GKGKTVVTSIHQPSSRVFQMFDTVLLLSEGKCLFVGKGRDAMAYFESVGFSPAFPMNPADFLLDL 319

  Fly   356 ACGEYGYDKV----------------DTLKLATENGSCLTWFHNPSAVLRAEVLMRKYPIPKKTK 404
            |.|....|.|                ||| ||.:..:|:...|.|....|.            .|
plant   320 ANGVCQTDGVTEREKPNVRQTLVTAYDTL-LAPQVKTCIEVSHFPQDNARF------------VK 371

  Fly   405 SR-------SLEDTSYSNQCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSR 462
            :|       :...|.:|..| :||.| .:|.:|..:...|||...:|.:.|.|.|:.|:  :...
plant   372 TRVNGGGITTCIATWFSQLC-ILLHR-LLKERRHESFDLLRIFQVVAASILCGLMWWHS--DYRD 432

  Fly   463 VLDNYNLLFAILMHHSMTTMMLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCF 527
            |.|...|||.|.:...:......|.|||.:.:|..:|..:..|:|.:|:.|..|..|.:.::...
plant   433 VHDRLGLLFFISIFWGVLPSFNAVFTFPQERAIFTRERASGMYTLSSYFMAHVLGSLSMELVLPA 497

  Fly   528 FFTVIVYLWSYQPMEWIRFFMFFSISLLTVFVGHSFGLMIGAWFDVVNGTFLAPVLTIPMMMF-- 590
            .|....|...|.....:.|.:..|:.||.|......||.:||  .:::....:.::|:.|:.|
plant   498 SFLTFTYWMVYLRPGIVPFLLTLSVLLLYVLASQGLGLALGA--AIMDAKKASTIVTVTMLAFVL 560

  Fly   591 AGFGVTLRDLPSYLRWGSHIS----------YLRYGLEGFISAIYGLD----RGTLACEEAPYCH 641
            .| |..:..:||.:.|..::|          .::||....|..:.|.|    :|..|...|. |
plant   561 TG-GYYVNKVPSGMVWMKYVSTTFYCYRLLVAIQYGSGEEILRMLGCDSKGKQGASAATSAG-C- 622

  Fly   642 YRYPKKFLEEITMRGDQFWNDVIALGVMILVFRFVSYVVLKAKIK 686
                 :|:||..:.....|..|..|.:|...:|.::|:.|: :||
plant   623 -----RFVEEEVIGDVGMWTSVGVLFLMFFGYRVLAYLALR-RIK 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	183/661 (28%)
		ABCG_EPDR	102..326	CDD:213180	83/253 (33%)
		ABC2_membrane	420..623	CDD:279410	55/214 (26%)
ABCG25	NP_565030.1	PLN03211	1..662	CDD:215634	191/695 (27%)
		ABCG_EPDR	70..290	CDD:213180	77/220 (35%)
		ABC2_membrane	393..592	CDD:279410	52/204 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720