DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and ABCG16

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_191069.2	Gene:	ABCG16 / 824675	AraportID:	AT3G55090	Length:	736	Species:	Arabidopsis thaliana

Alignment Length:	706	Identity:	171/706 - (24%)
Similarity:	303/706 - (42%)	Gaps:	114/706 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 EEEVH--FDTDAL------NNLPAREPVDMEFKELSLTV----KLGFN----------RGSKEIL 126
            |..||  ||.|..      ::|....|..:.|..|:..|    ||.|:          ..:|.:|
plant    44 ETPVHEFFDRDGSSLDGDNDHLMRPVPFVLSFNNLTYNVSVRRKLDFHDLVPWRRTSFSKTKTLL 108

  Fly   127 HNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTG-VDGSILLNGRRRDLPSFRRMSCYITQD 190
            .|:.|:....:::|::|.||:|||||:|||:.....| :.|::.|||........:.:|.|:.||
plant   109 DNISGETRDGEILAVLGASGSGKSTLIDALANRIAKGSLKGTVTLNGEALQSRMLKVISAYVMQD 173

  Fly   191 DRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTLT-----MRLSGGQKK 250
            |.|.|:|||.|.:..||:.:|.:::...:|:.|::.::..||:.|..:|:.     ..:|||:::
plant   174 DLLFPMLTVEETLMFAAEFRLPRSLPKSKKKLRVQALIDQLGIRNAAKTIIGDEGHRGISGGERR 238

  Fly   251 RLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQVY 315
            |:||.:::|::|.|:||||||:||||:|...|:::||::...|..||.:||||:.::..:.|::.
plant   239 RVSIGIDIIHDPIVLFLDEPTSGLDSTSAFMVVKVLKRIAESGSIIIMSIHQPSHRVLSLLDRLI 303

  Fly   316 VLSAGNCVYQGSTQKLVPFLQSVDLPCPMYHNPADYIIEL-------ACGEYG---YDKVDTLKL 370
            .||.|:.|:.||...|..|......|.|...|..::.::|       |.|..|   ::|......
plant   304 FLSRGHTVFSGSPASLPSFFAGFGNPIPENENQTEFALDLIRELEGSAGGTRGLVEFNKKWQEMK 368

  Fly   371 ATENGSCLT--WFHNPSAVLRAEVLMRKYPIPKKTKSR-------------------SLEDTSYS 414
            ...|...||  ...||:..|:..:        ..:.||                   :|...:::
plant   369 KQSNPQTLTPPASPNPNLTLKEAI--------SASISRGKLVSGGGGGSSVINHGGGTLAVPAFA 425

  Fly   415 N----QCSVLLRRGFIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSRVLDNYNLLFAILM 475
            |    :...|.||..:.::|...:..:|:...|....:...::.........|.:... .||.
plant   426 NPFWIEIKTLTRRSILNSRRQPELLGMRLATVIVTGFILATVFWRLDNSPKGVQERLG-FFAF-- 487

  Fly   476 HHSMTTMMLT----VLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVYLW 536
              :|:||..|    :..|..:..|.::|.....|...:|..:..:|..|..|.....|.|..: |
plant   488 --AMSTMFYTCADALPVFLQERYIFMRETAYNAYRRSSYVLSHAIVTFPSLIFLSLAFAVTTF-W 549

  Fly   537 SYQPMEWIRFFMFFSISLLTVF-VGHSF-GLMIGAWFDVVNGTFLAPVLTIPMMMFAGFGVTLRD 599
            :......:..|:|:.:.:|..| .|.|| ..:.|....|:.|..:...:....::|:||.:....
plant   550 AVGLEGGLMGFLFYCLIILASFWSGSSFVTFLSGVVPHVMLGYTIVVAILAYFLLFSGFFINRDR 614

  Fly   600 LPSYLRWGSHISYLRYGLEGFISAIYG-----LDRGTLACEEAPYCHYRYPKK--FLEEI----- 652
            :|.|..|..::|.::|..|..:...:.     ..||....:.:|.....|..|  .|:.:
plant   615 IPQYWIWFHYLSLVKYPYEAVLQNEFSDPTECFVRGVQLFDNSPLGELTYGMKLRLLDSVSRSIG 679

  Fly   653 ---------TMRGDQF----------WNDVIALGVMILVFRFVSYVVLKAKIKSIR 689
                     |...|..          ||.::.......:||.:.|:.|....|:.|
plant   680 MRISSSTCLTTGADVLKQQGVTQLSKWNCLLITVGFGFLFRILFYLCLLLGSKNKR 735

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	164/683 (24%)
		ABCG_EPDR	102..326	CDD:213180	83/243 (34%)
		ABC2_membrane	420..623	CDD:279410	43/208 (21%)
ABCG16	NP_191069.2	3a01204	75..735	CDD:273361	162/673 (24%)
		P-loop_NTPase	85..314	CDD:304359	79/228 (35%)
		ABC2_membrane	435..638	CDD:279410	43/208 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820