DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5853 and ABCG37

DIOPT Version :9

Sequence 1:	NP_001260309.1	Gene:	CG5853 / 34322	FlyBaseID:	FBgn0032167	Length:	689	Species:	Drosophila melanogaster
Sequence 2:	NP_190916.1	Gene:	ABCG37 / 824516	AraportID:	AT3G53480	Length:	1450	Species:	Arabidopsis thaliana

Alignment Length:	660	Identity:	166/660 - (25%)
Similarity:	308/660 - (46%)	Gaps:	105/660 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 TNGNEPSKQPPLEPVVEEEVHFDTDALNNLPAREPVDMEFKELSLTVKL-------GFNRGSKEI 125
            |..:...|:....||..||    .|.: .||.: |:.:.|::|:..|.:       |:::...::
plant   819 TEDSSVRKKTTDSPVKTEE----EDKM-VLPFK-PLTVTFQDLNYFVDMPVEMRDQGYDQKKLQL 877

  Fly   126 LHNVCGKFPGSQLIAIMGPSGAGKSTLLDALSGFKTTG-VDGSILLNGRRRDLPSFRRMSCYITQ 189
            |.::.|.|....|.|:||.|||||:||||.|:|.||:| ::|.|.::|..:...:|.|:|.|..|
plant   878 LSDITGAFRPGILTALMGVSGAGKTTLLDVLAGRKTSGYIEGDIRISGFPKVQETFARVSGYCEQ 942

  Fly   190 DDRLQPLLTVNENMHIAADLKLGQTVSYEEKESRIEDILLLLGLYNHDQTL-----TMRLSGGQK 249
            .|...|.:||.|::..:|.|:|...:....|...::.:|..:.|.....:|     ...||..|:
plant   943 TDIHSPNITVEESVIYSAWLRLAPEIDATTKTKFVKQVLETIELDEIKDSLVGVTGVSGLSTEQR 1007

  Fly   250 KRLSIAMELINNPTVMFLDEPTTGLDSSSCTKVLELLKKLTSQGRTIICTIHQPTAKLFQIFDQV 314
            |||:||:||:.||:::|:||||||||:.:...|:..:|.:...||||:||||||:..:|:.||::
plant  1008 KRLTIAVELVANPSIIFMDEPTTGLDARAAAIVMRAVKNVADTGRTIVCTIHQPSIDIFEAFDEL 1072

  Fly   315 YVLS-AGNCVYQG----STQKLVPFLQSV-DLP-CPMYHNPADYIIELACG----EYGYDKVDTL 368
            .:|. .|..:|.|    .::.::.:.:|| ::| ....||||.::::::..    |.|   ||..
plant  1073 VLLKRGGRMIYTGPLGQHSRHIIEYFESVPEIPKIKDNHNPATWMLDVSSQSVEIELG---VDFA 1134

  Fly   369 KLATENGSCLTWFHNPSAVLRAEVLMRKYPIP---------KKTKSRSLEDTSYSNQCSVLLRRG 424
            |:          :|:.:...|...|:::...|         |:|.::     |:..|...:|.:.
plant  1135 KI----------YHDSALYKRNSELVKQLSQPDSGSSDIQFKRTFAQ-----SWWGQFKSILWKM 1184

  Fly   425 FIKAKRDTTMTHLRIGVNIAVAALFGAMYDHTGREGSRVLDN-------YNLLFAILMHHSMTTM 482
            .:...|..:...:|:...:..:.:|||::...|:.    ||.       :..::.:::...:...
plant  1185 NLSYWRSPSYNLMRMMHTLVSSLIFGALFWKQGQN----LDTQQSMFTVFGAIYGLVLFLGINNC 1245

  Fly   483 MLTVLTFPMDISILIKEHFNRWYSLKAYYTAMTLVDLPISIISCFFFTVIVY-LWSYQPMEWIRF 546
            ...:..|..:.:::.:|.|...||..||.....:.::|...|....|.::.| :..:.|..:..|
plant  1246 ASALQYFETERNVMYRERFAGMYSATAYALGQVVTEIPYIFIQAAEFVIVTYPMIGFYPSAYKVF 1310

  Fly   547 FMFFSI--SLLTVFVGHSFGLMIGAWFDVVNGTFLAPVLTIPMMMFAGFGVTLRDLPSYLRWGSH 609
            :..:|:  ||||......|.:.|...|.|  ...|..:..:...:|:||.:....:|.:..|..:
plant  1311 WSLYSMFCSLLTFNYLAMFLVSITPNFMV--AAILQSLFYVGFNLFSGFLIPQTQVPGWWIWLYY 1373

  Fly   610 ISYLRYGLEGFISAIYGLDRGTLACEEAPYCHYRYPKKFLEEITMRGDQ------------FWND 662
            ::...:.|.||||:.||                    ...|||.:.|..            |.:|
plant  1374 LTPTSWTLNGFISSQYG--------------------DIHEEINVFGQSTTVARFLKDYFGFHHD 1418

  Fly   663 VIALGVMILV 672
            ::|:..::.:
plant  1419 LLAVTAVVQI 1428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5853	NP_001260309.1	3a01204	97..689	CDD:273361	159/631 (25%)
		ABCG_EPDR	102..326	CDD:213180	85/237 (36%)
		ABC2_membrane	420..623	CDD:279410	41/212 (19%)
ABCG37	NP_190916.1	PLN03140	54..1450	CDD:215599	166/660 (25%)
		ABC_trans_N	89..167	CDD:291196
		ABCG_PDR_domain1	186..429	CDD:213200
		ABC2_membrane	530..735	CDD:279410
		PDR_assoc	742..804	CDD:285559
		ABCG_PDR_domain2	847..1085	CDD:213199	85/237 (36%)
		ABC2_membrane	1180..1387	CDD:279410	41/212 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910